Results 41 to 50 of about 319,874 (307)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Dimensionality and consequences of service innovation: An empirical study of hospitality industry

open access: yesCogent Business & Management, 2021
Based on service dominant logic (SDL) and resource-based view (RBV), this study investigates the impact of service innovation-underlying dimensions, namely, technological innovation, organizational innovation and human capital innovation on market ...
Dada Ab Rouf Bhat, Vivek Sharma
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Innovation Prioritization Decisions in the Product–Service Supply Chain: The Impact of Data Mining and Information Sharing Strategies

open access: yesMathematics
Driven by the servicing and digital transformation of manufacturing enterprises, product and service innovation for manufacturers and service providers to promote integrated solutions collaboratively has become an important way for enterprises to ...
Jinfa Shi, Wei Liu, Yongqiang Su
doaj   +1 more source

Identification of Service Innovation Dimensions in Service Organizations [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2015
In today competitive world, innovation is a key factor for creating competitive advantage and even for survival of the enterprises and as a propellant for business growth and prosperity and maintain more profitability for an organization, as a result of ...
Mohammad Meigounpoory   +2 more
doaj  

Open Services Innovation: The Case of BT in the UK

open access: yesJournal of Technology Management & Innovation, 2014
Open innovation was conceptualised by Chesbrough (2003, p. 34) using cases from the ICT (Information and Communications Technologies) sector, more specifically equipment and component suppliers such as Lucent, IBM and Intel.
Carlos Eduardo Yamasaki Sato
doaj   +1 more source

Users as service innovators: The case of banking services [PDF]

open access: yesResearch Policy, 2010
Many services can be self-provided. An individual user or a user firm can, for example, choose to do its own accounting - choose to self-provide that service - instead of hiring an accounting firm to provide it. Since users can 'serve themselves' in many cases, it is reasonable to suspect that they can also innovate with respect to the services they ...
Oliveira, Pedro, Hippel, Eric Von
openaire   +1 more source

Service innovation in sustainable product service systems: improving performance under linguistic preferences

open access: yes, 2018
Sustainable product service systems enable firms that are operating under resource limitations to deliver the best possible outcomes in terms of social well-being and economic growth.
Chiu, Anthony S. F.   +7 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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