Results 91 to 100 of about 84,201 (264)

Association of phenotypic traits and fertility in Holstein heifers: Body condition score, body weight, antral follicle count, anti-Müllerian hormone, and anogenital distance

Journal of Dairy Science
: The aim of this cross-sectional observational study was to assess whether nulliparous Holstein heifer fertility is associated with (1) energy reserve-related traits, such as BCS and BW; (2) ovarian reserve-related traits, such as anti-Müllerian hormone
Andréia Ferreira Machado, Leticia P. Sanglard, Santiago Andres Paez Hurtado, João Victor Chaves, Muhammad Awais Ajmal, José Domingos Guimarães, Jeffrey S. Stevenson, Simone E.F. Guimarães, Victor E. Gomez-Leon   +8 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Kisaran Service Per Conception (S/C) Sapi Peranakan Ongole (PO) di Desa Srimulyo Kecamatan Kalirejo Kabupaten Lampung Tengah

wahana peternakan, 2020
in Srimulyo village, Kalirejo District, Central Lampung Regency was conducted in January 2019 until February 2019. The material submitted in the reseach are 200 Ongole Cross-breed cows. The variable research is Service per Conception (S/C). The method used in this research is to collect primary and secondary data.
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Polymorphism in the Exon 11 of Bovine Luteinizing Hormone Receptor Gene and its Association with Service per Conception in Pasundan Cows [PDF]

Pakistan Journal of Zoology, 2021
Syahruddin Said, Widya Pintaka Bayu Putra, Dani Nur Arifin   +2 more
openaire   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Tingkat Pengetahuan Peternak Tentang Gejala Birahi dan Service Per Conception pada Sapi Peranakan Ongole

JDP: Jurnal Dunia Peternakan
Tujuan penelitian ini adalah untuk mengetahui tingkat pengetahuan peternak tentang gejala birahi dan service per conception sapi PO di Desa Sidorejo Kecamatan Sidomulyo Kabupaten Lampung Selatan. Materi dari peternak dan inseminator yakni catatan reproduksi induk sapi PO sebanyak 90 ekor.
openaire   +1 more source