Results 31 to 40 of about 5,356,878 (308)
The transition towards service-oriented business models
International Journal of Engineering Business Management, 2018 New trends for capital goods manufacturers push towards selling the products usage or performance rather than the product itself. This evolution from traditional business models, based on the product sales, to new service-oriented business models (BMs ...
Federico Adrodegari +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
LHB Hydroscience JournalEn France, le Ministère de la Transition Ecologique avec Vigicrues fournis une information sur le risque de crues à venir dans les prochaines 24 h (Vigilance Crue) sur plus de 20000km de cours d’eau.
Didier Narbais-Jaureguy +9 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Global ecosystem service values in climate class transitions
Environmental Research Letters, 2020 Ecosystem service assessments facilitate the valuation of nature and support decision-making. Ecosystem services are connected to climate; however, ecosystem service values affected by climate change remain unclear.
Lisa Watson +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Research Findings from Service Users and Service Providers [PDF]
, 2017 The HSE is committed to achieving a decisive shift towards stronger, more integrated Primary Care services. To identify opportunities to enhance GP and Primary Care services, a series of consultations and engagements was undertaken to understand ‘what ...
Health Service Executive (HSE)
core +1 more source
International Journal of Africa Nursing Sciences, 2022 Aim: The study addresses transition support needs of nurse graduates during their compulsory community service, giving the perspectives of nurse graduates, hospital managers, and mentors.
Nicholin Scheepers +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Water Resources and IndustryThe rapid industrialisation and urbanisation in recent decades have significantly increased global wastewater generation, particularly in industrial parks.
Nur Hairunnisa Rafaai +8 more
doaj +1 more source