Results 61 to 70 of about 5,356,878 (308)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Business Implications of Integrated Product and Service Offerings [PDF]
, 2009 Organised by: Cranfield UniversityThis paper explores the business implications of Integrated Product and Service Offerings (IPSOs). The objective is to show examples of the business implications of IPSOs from a supplier’s perspective, and to suggest ...
Lindahl, Mattias +5 more
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Newly employed nurses’ transition into their new role in the ambulance service– a qualitative study
BMC NursingBackground Nurses are essential to ensure safe and high-quality care worldwide. The World Health Organization (WHO) forecasts a shortfall of 5.9 million nurses by the year 2030, and in the ambulance service, the turnover rate ranges between 20% and 30 ...
Klara Jepsen +3 more
doaj +1 more source
Organizational Change: The Experiences of Practitioners Transitioning to a Fee-for-Service Model
Journal of Human Services: Training, Research, and Practice, 2020 Many human service agencies are in the midst of a transition for a fee-for-service model. Through the midst of the transition, organizations must shift the culture of their agency and adapt to the new service delivery approach.
Anthony Zazzarino +2 more
doaj
Journal of College Orientation, Transition, and Retention, 2010 The Service Leadership Seminar program at Florida State University is a unique way to assist first-year students with their transition to college while enabling them to continue their commitment to service and leadership. This article explores the impact
Kathy L. Guthrie
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Frontiers in Rehabilitation SciencesBackgroundWhen transitioning to adulthood, youth with disabilities and their families face many service gaps. Successful inter-agency collaborations can promote family-centred, inclusive transition support amenable to personal choice and health ...
Yukari Seko +5 more
doaj +1 more source
Measurement and description of nursing-care service process
Nihon Kikai Gakkai ronbunshu, 2015 Employees at nursing-care facilities co-operate with each other and provide nursing-care service according to care plans designed to meet residents’ physical condition and needs.
Hiroyasu MIWA +4 more
doaj +1 more source
The Barriers and Enablers of Primary Healthcare Service Transition From Government to Community Control in Yarrabah: A Grounded Theory Study. [PDF]
Front Public Health, 2021 McCalman J +5 more
europepmc +1 more source