Results 91 to 100 of about 362,664 (315)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Frontiers in PsychiatryIntroductionMental health is influenced by how we perceive ourselves and others. A person’s conceptual structure and how he/she understands and makes sense of the world can be explored using the repertory grid technique (RGT), an assessment tool derived ...
Eleanor Elizabeth Wozniak +7 more
doaj +1 more source
Service Selection With QoS Correlations in Distributed Service-Based Systems
IEEE Access, 2019 Service selection is an important research problem in distributed service-based systems, which aims to select proper services to meet user requirements. A number of service selection approaches have been proposed in recent years.
Dongwei Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Experiences of service user involvement and their influence on identity [PDF]
, 2015 Identity can be considered to be socially constructed and developed through narratives about ourselves and our experiences. Having socially valued roles may thus facilitate a positive identity.
Emery, L.
core
The experience of mental health service users in health system strengthening: lessons from Uganda
International Journal of Mental Health Systems, 2019 Background Mental, neurological and substance use disorders are a public health burden in Uganda. Mental health service user involvement could be an important strategy for advocacy and improving service delivery, particularly as Uganda redoubles its ...
James Mugisha +6 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Service users' views of self-help strategies and research in the UK
, 2007 Background: Self-help approaches for mental health problems are a research and service development priority within the UK. Aim: To engage service users in the research process through a consultation exercise, seek their views on the strategies they ...
Jones, Anthony +3 more
core +1 more source
Optimising Capacity – A Service User and Caregiver Perspective on Reablement
Grounded Theory Review: An International Journal, 2016 Reablement focuses on offering individuals the opportunity to regain independence and thus stay longer in their homes. Few studies have looked at service users and caregivers’ perspectives on reablement.
Cathrine Moe, Berit Støre Brinchmann
doaj