Results 81 to 90 of about 362,664 (315)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Supporting Mobile Service Usage through Physical Mobile Interaction [PDF]
, 2007 Although mobile services can be used ubiquitously, their employment and the interaction with them are still restricted by the constraints of mobile devices.
Schmidt, Albrecht +13 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A Methodology of Persona-centric Service Design [PDF]
, 2009 Organised by: Cranfield UniversityIn order to clarify the customer’s inclination and provide them with better services, the persona-scenario method has been accepted in Requirements Engineering.
Hara, T. +4 more
core
An exploration of service user involvement in the assessment of students
, 2015 Introduction: This paper is an exploration of service user involvement in assessing first year diagnostic radiography students' ability to practise and interact with the public safely prior to attending placement. Service users took the role of patients
Naylor, Sarah +4 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Perceived Improvements in Service User Involvement in Two Clinical Psychology Training Courses
, 2010 In line with current developments in mental health training, the doctoral courses in clinical psychology at two UK universities, Canterbury Christ Church and Surrey, have been working together to increase service user and carer involvement.
Holttum, S. +3 more
core +1 more source
A Survey of User Profiling: State-of-the-Art, Challenges, and Solutions
IEEE Access, 2019 Advancements in information and communication technology, and online web users have given attention to the virtual representation of each user, which is crucial for effective service personalization.
Christopher Ifeanyi Eke +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2013 Background: The efficacy of interventions and treatments for self-harm is well researched. Previous reviews of the literature have highlighted the lack of definitively effective interventions for self-harm and have highlighted the need for future ...
Ward, J, De Motte, C, Bailey, D
core +1 more source