Results 61 to 70 of about 362,664 (315)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

User Parameter Tunning for VoD Service Users [PDF]

, 2003
This work has been focused on the design of a VoD parameter-measuring tool. This tool works as a video client and additionally provides a set of measurements used to define different user parameters in different network conditions.
A. Echavarren, C. Zubieta, Jesús E. Villadangos, Manuel Prieto 0002   +3 more
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Service user or service provider? How social work and human service students integrate dual identities

, 2017
Students studying undergraduate social work and human services (SWHS) degrees may have used health and human service agencies, before and during their university education.
Burton, Judith, Edwards, Niki, Niki Edwards, Newcomb, Michelle, Michelle Newcomb, Judith Burton   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Service Recommendation Method Based on Trusted Similar User [PDF]

Jisuanji gongcheng, 2016
It is increasingly important to perform service recommendation as increasingly more users and services are involved in service computing,but some inauthentic service evaluations from a few users decrease the dependability and effectiveness of service ...
WU Wenming,LIU Xiping
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Mental health and human rights : a common agenda for user/survivor and women’s groups? [PDF]

, 2009
Mental health is set to be an important agenda for the new Equalities and Human Rights Commission in the UK, providing a significant opportunity for coalescing the work of mental health service user/survivor and women’s groups.
Lewis, Lydia
core   +1 more source

Orientations of professional discretion in the welfare service state

Social Work and Society, 2019
The idea of discretion has re-emerged as a positive attribute of professional practice in policy in the welfare service state. Flexibility and a consumer orientation have given rise to a new discourse of professionalism as a service orientation, which ...
Tony Evans
doaj   +2 more sources