Results 91 to 100 of about 58,076 (334)

Vulnerability assessment of the S. João de Loure Bridge: Vouga’s river [PDF]

open access: yes, 2005
Steel bridges are particularly sensible to corrosion, which can put at risk the structural safety by affecting the joint elements. Having this in mind, the objective of this work was to evaluate the influence of the joint's stiffness in the structural ...
Fernandes, C., Varum, H.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Experimental Investigation on Flexural Crack Control for High-Strength Reinforced-Concrete Beam Members

open access: yesInternational Journal of Concrete Structures and Materials, 2018
The purpose of this study is to investigate the flexural crack development of high-strength reinforced concrete (HSRC) beams and suggest the design equations of the flexural crack control for HSRC beams. This study conducts two full-size simply-supported
Chien-Kuo Chiu, Kai-Ning Chi, Bo-Ting Ho
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Deep Temporal LSTM Regression Network (DTLR-Net) Model for Optimizing Quality of Video Streaming Quality in CDN-P2P Model

open access: yesIEEE Access
Due to the increasing popularity of live streaming, the need for more efficient and effective content delivery servers has become more prevalent. With the help of the latest generation of streaming models, such as the Content Delivery Network (CDN), it ...
Satyanarayanareddy Marri   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Life-Cycle Cost Analysis in Pavement Management System

open access: yesCommunications, 2013
Pavement Management System (PMS) is a set of methods and tools which allow for optimal allocation of limited resources while keeping the road network in serviceable condition.
Jan Mikolaj   +2 more
doaj   +1 more source

S. João de Loure Bridge: vulnerability assessment and study of a common strengthening solution [PDF]

open access: yes, 2005
This paper presents a structural vulnerability assessment of the steel bridge S. João de Loure. A structural model of the bridge was created and the influence of the joint’s stiffness on its structural response was evaluated using the structural analysis
Fernandes, C., Varum, H.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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