Results 101 to 110 of about 6,280,398 (285)

Department of Administrative Services (DAS) program on resident bidders under Public Act 11-229

open access: yes, 2012
"Pursuant to the provisions of section 9 of Public Act 11-229, the Department of Administrative Services (DAS) in consultation with the Commissioner of Labor, the President of the University of Connecticut, the Commissioner of Public Works (now the ...
Connecticut. Dept. of Administrative Services.
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Le attività di NAIS e la piattaforma Web sviluppata per il progetto ArTeK

open access: yesArcheomatica, 2018
NAIS Nextant Applications and Innovative Services
doaj   +3 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Other title: KanCare 101

open access: yes, 2017
January 18, 2017. Committee name and date taken from Kansas Legislature website.; Presentation before the Kansas Legislature, House Social Services Budget Committee, presented by the Kansas Department for Aging and Disability Services.Presentation ...
Kansas. Department for Aging and Disability Services.
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Annual report/ Connecticut Department of Revenue Services. FY 2012-2013.

open access: yes, 2013
Annual; Fiscal years 2003/2004 and 2004/2005 combined.; Report year ends June 30.; Prepared by the Dept.
Connecticut. Department of Revenue Services.
core   +1 more source

Annual report/ Connecticut Department of Revenue Services. FY 2011-2012.

open access: yes, 2012
Annual; Fiscal years 2003/2004 and 2004/2005 combined.; Report year ends June 30.; Prepared by the Dept.
Connecticut. Dept. of Revenue Services.
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

A guide to services for senior citizens of Connecticut

open access: yes, 2006
Electronic data.; Title from PDF p. 1 (viewed Dec. 27, 2006).; Originally published: A guide to services for Connecticut's senior citizens / prepared by the State Department on Aging ; with the generous assistance of the Travelers.

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