Results 111 to 120 of about 1,480,406 (295)
Frontiers in NutritionBackgroundCoenzyme Q10 (CoQ-10) plays a vital role in cellular energy production and protection against oxidative stress. However, its absorption from orally administered forms is limited due to its poor water solubility and relatively large molecular ...
Ralf Jäger +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Correctness of services and their composition
, 2010 Wir studieren die Korrektheit von Services und Servicekompositionen und untersuchen, wie der Entwurf von korrekten Servicekompositionen systematisch unterstützt werden kann. Wir legen dabei den Fokus auf das Kommunikationsprotokoll der Services. Mithilfe von formalen Methoden tragen wir zu drei Szenarien von SOC bei.
openaire +3 more sources
Domain QoS and resource-aware logistics web service dynamic optimal composition
工程科学学报, 2018 With the rapid development of service computing, cloud computing, internet of things, e-commerce, and modern logistics industry, cross-domain logistics services cooperation has become the main development trend of the modern logistics industry.
XU Yuan-yuan, LIU Zhi-zhong, JIA Zong-pu
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Mediation of semantic web services in IRS-III [PDF]
, 2005 Business applications composed of heterogeneous distributed components or Web services need mediation to resolve data and process mismatches at runtime.
Cabral, Liliana, Domingue, John
core +1 more source
Energy-Efficient Composition of Configurable Internet of Things Services
IEEE Access, 2017 Along with the adaptation of Internet of Things (IoT) to support various industrial applications, the cooperation and coordination of smart things is a promising strategy for satisfying requirements that are beyond the capacity of any single smart thing.
Mengyu Sun +4 more
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Supporting the semi-automatic acquisition of semantic RESTful service descriptions [PDF]
, 2009 This paper presents SWEET: Semantic Web sErvices Editing Tool, the first tool developed for the semi-automatic acquisition of semantic RESTful service descriptions, aiming to support a higher level of automation of common RESTful service tasks, such as ...
Domingue, John +3 more
core +1 more source