Results 31 to 40 of about 62,684 (286)

Functional Characterization and Expression Analysis of Terpene Synthase Genes HcTPS9 and HcTPS6 in Hedychium coronarium

open access: yesGuangdong nongye kexue
【Objective】The rhizomes and flowers of Hedychium coronarium are rich in terpenoid essential oils with diverse bioactivities, including anti-inflammatory, analgesic, and antimicrobial properties.
Yuechong YUE   +5 more
doaj   +1 more source

Linking Terpene Synthases to Sesquiterpene Metabolism in Grapevine Flowers

open access: yesFrontiers in Plant Science, 2019
Grapevine (Vitis vinifera L.) terpene synthases (VviTPS) are responsible for the biosynthesis of terpenic volatiles. Volatile profiling of nine commercial wine cultivars showed unique cultivar-specific variation in volatile terpenes emitted from ...
Samuel Jacobus Smit   +2 more
doaj   +1 more source

A Comprehensive In Silico Study of New Metabolites from Heteroxenia fuscescens with SARS-CoV-2 Inhibitory Activity

open access: yesMolecules, 2022
Chemical investigation of the total extract of the Egyptian soft coral Heteroxenia fuscescens, led to the isolation of eight compounds, including two new metabolites, sesquiterpene fusceterpene A (1) and a sterol fuscesterol A (4), along with six known ...
Fahd M. Abdelkarem   +11 more
doaj   +1 more source

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]

open access: yes, 2013
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison   +3 more
core   +2 more sources

Anthoteibinenes F–Q: New Sesquiterpenes from the Irish Deep-Sea Coral Anthothela grandiflora

open access: yesMarine Drugs
New technology has opened opportunities for research and exploration of deep-water ecosystems, highlighting deep-sea coral reefs as a rich source of novel bioactive natural products.
Stine S. H. Olsen   +6 more
doaj   +1 more source

Brominated Selinane Sesquiterpenes from the Marine Brown Alga Dictyopteris divaricata

open access: yesMarine Drugs, 2009
Two new brominated selinane sesquiterpenes, 1-bromoselin-4(14),11-diene (1) and 9-bromoselin-4(14),11-diene (2), one known cadinane sesquiterpene, cadalene (3), and four known selinane sesquiterpenes, α-selinene (4), β-selinene (5), β-dictyopterol (6 ...
Hua-Ling Xiao   +5 more
doaj   +1 more source

Chemistry and Bioactivity of the Deep-Water Antarctic Octocoral Alcyonium sp.

open access: yesMarine Drugs, 2022
Chemical investigation of an Antarctic deep-water octocoral has led to the isolation of four new compounds, including three illudalane sesquiterpenoids (1–3) related to the alcyopterosins, a highly oxidized steroid, alcyosterone (5), and five known ...
Anne-Claire D. Limon   +6 more
doaj   +1 more source

Smallanthus sonchifolius (Yacon) leaves: an emerging source of compounds for diabetes management [PDF]

open access: yes, 2015
Diabetes mellitus is a chronic metabolic disease that develops mainly due to insulin deficiency or resistance to insulin action. All forms of diabetes are characterized by chronic hyperglycemia, which has an important role in the pathogenesis of diabetic
Genta, Susana Beatriz de Fátima   +2 more
core  

Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.) [PDF]

open access: yes, 2013
Chicory (Cichorium intybus) has been shown to induce enzymes of pharmacokinetic relevance (cytochrome P450; CYP). The aim of this study was to investigate the effects of selected secondary plant metabolites with a global extract of chicory root, on the ...
Ekstrand, Bo   +2 more
core   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

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