Results 41 to 50 of about 63,391 (300)
Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Chemistry and Bioactivity of the Deep-Water Antarctic Octocoral Alcyonium sp.
Marine Drugs, 2022 Chemical investigation of an Antarctic deep-water octocoral has led to the isolation of four new compounds, including three illudalane sesquiterpenoids (1–3) related to the alcyopterosins, a highly oxidized steroid, alcyosterone (5), and five known ...
Anne-Claire D. Limon +6 more
doaj +1 more source
Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]
, 2013 Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison +3 more
core +2 more sources
Sesquiterpenes and oxygenated sesquiterpenes dominate the emissions of downy birches [PDF]
, 2020 Abstract. Even though isoprene and monoterpene (MT) emissions of boreal needle trees have been studied quite intensively, there is less knowledge on the emissions of broadleaved deciduous trees and emissions of larger terpenes and oxygenated volatile organic compounds (OVOCs).
Heidi Hellén +7 more
openaire +1 more source
Advanced Science, EarlyView.This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source
Molecules, 2006 A review of results of bioactivity and reactivity examinations of marine sesquiterpene (hydro)quinones is presented. The article is focused mostly on friedo- rearranged drimane structural types, isolated from sponges of the order Dictyoceratida. Examples
Miroslav J. Gasic, Dusan Sladic
doaj +1 more source
Emissions of volatile organic compounds from Norway spruce and potential atmospheric impacts
Frontiers in Forests and Global Change, 2023 Published biogenic volatile organic compound (BVOC) emission rates of Norway spruces vary a lot. In this study we combined published Norway spruce emission rates measured in boreal forests and added our new, unpublished emission data from Southern (SF ...
Hannele Hakola +9 more
doaj +1 more source
Xanthium strumarium - a potential cheap resource of plant substances for medicinal use [PDF]
, 2019 Xanthium strumarium L. (Asteraceae) is an annual herb which reproduces solely by seed. So far its centre of origin was considered Central or South America. Recent archeological research revealed that the burs of X.
Ionkova I., Kozuharova E., Spadaro V.
core +1 more source
Chemistry – A European Journal, EarlyView.Males of the tropical frog Gephyromantis granulatus carry unique ethyl‐branched sesquiterpenoid macrolactones in their scent glands. Their structure elucidation was performed by GC/MS, leading to the proposed structures of the granolides. A flexible enantioselective synthesis confirmed the structures and allowed determination of their absolute ...
Johanna Kuhn +2 more
wiley +1 more source
Open Chemistry, 2018 Redbay ambrosia beetle, Xyleborus glabratus, is native to Southeast Asia, but subsequent to introduction in Georgia in 2002, it has become a serious invasive pest in the USA, now established in nine southeastern states. Females vector Raffaelea lauricola,
Kendra Paul E. +5 more
doaj +1 more source