Parthenin-A Sesquiterpene Lactone with Multifaceted Biological Activities: Insights and Prospects. [PDF]
Parthenin, a sesquiterpene lactone of pseudoguaianolide type, is the representative secondary metabolite of the tropical weed Parthenium hysterophorus (Asteraceae).
Kaur A+7 more
europepmc +2 more sources
Costunolide-A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential. [PDF]
Sesquiterpene lactones constitute a major class of bioactive natural products. One of the naturally occurring sesquiterpene lactones is costunolide, which has been extensively investigated for a wide range of biological activities.
Kim DY, Choi BY.
europepmc +2 more sources
Successful treatment of airborne allergic dermatitis to sesquiterpene lactone with upadacitinib: A case report [PDF]
This case report describes, to our knowledge, the first known successful treatment of airborne allergic contact dermatitis to sesquiterpene lactone with upadacitinib in an adult patient.
Barbara Marzario+2 more
doaj +2 more sources
Brevilin A, a Sesquiterpene Lactone, Inhibits the Replication of Influenza A Virus In Vitro and In Vivo. [PDF]
With the emergence of drug-resistant strains of influenza A viruses (IAV), new antivirals are needed to supplement the existing counter measures against IAV infection.
Zhang X+5 more
europepmc +2 more sources
Plant sesquiterpene lactones [PDF]
Sesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the ecological significance of STLs, highlighting their roles in plant defense mechanisms against herbivory and as phytotoxins, alongside ...
Olivia Agatha+3 more
arxiv +4 more sources
Sesquiterpene lactones. Part XXII. Sesquiterpene lactones in Species of the Genus Chrysanthemum
A method of effective study on sesquiterpeine lactones in unknown plant material was worked out. This method allows the choice of species with high sesquiterpene lactones content and interesting chemical composition.
E. Błoszyk, B. Drożdż
doaj +4 more sources
Sesquiterpene lactones in chemotaxonomy
Abstract The utilization of guaianolides in chemotaxonomy is discussed, and some biosynthetic considerations are advanced.
Cornelius Steelink, Jeffrey C. Spitzer
openalex +3 more sources
Dehydrobrachylaenolide: an eudesmane-type sesquiterpene lactone [PDF]
The three-ring eudesmanolide, C15H16O3, is a natural product isolated from Dicoma anomala Sond. (Asteraceae). The compound contains an endo–exo cross conjugated methylenecyclohexenone ring with an envelope conformation trans-fused with cyclohexane ...
M. Rademeyer+2 more
doaj +5 more sources
Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer. [PDF]
The sesquiterpene lactones, Isodeoxyelephantopin (IDET) and Deoxyelephantopin (DET) are known to exhibit activities against some cancer types. The activities of these lactones against breast cancer and the molecular bases is not known.
Verma SS+6 more
europepmc +2 more sources
Dehydroleucodin: a guaiane-type sesquiterpene lactone [PDF]
Dehydroleucodin [systematic name: (1S,6S,2R)-9,13-dimethyl-5-methylene-3-oxatricyclo[8.3.0.02,6]trideca-9,12-diene-4,11-dione], C15H16O3, is a guanolide isolated from Artemisia douglasiana. The fused-ring system contains a seven-membered ring that adopts
Horacio A. Priestap+4 more
doaj +5 more sources