Results 91 to 100 of about 84,172 (271)

Isolation of a natural product with anti-mitotic activity from a toxic Canadian prairie plant

Heliyon, 2021
We are investigating plants from the prairie ecological zone of Canada to identify natural products that inhibit mitosis in cancer cells. Investigation of plant parts from the Canadian plant species Hymenoxys richardsonii (Asteraceae) revealed that leaf ...
Layla Molina, David E. Williams, Raymond J. Andersen, Roy M. Golsteyn   +3 more
doaj  

Sesquiterpene lactones from Tanacetum ferulaceum

Phytochemistry, 1990
2341
González, Antonio G., Bermejo, Jaime, Triana, Jorge, López Sánchez, Mariana, Eiroa, José L.   +4 more
openaire   +4 more sources

A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.

Carcinogenesis, 2013
Lung cancer is the leading cause of cancer deaths worldwide and current therapies fail to treat this disease in majority of cases. Antrodia camphorata is a medicinal mushroom being widely used as food dietary supplement for cancer prevention.
C. Yeh, Wen-Chien Huang, Y. Rao, M. Ye, Wei-Hwa Lee, Liang‐Shun Wang, David T. W. Tzeng, C. Wu, Y. Shieh, Chi-Ying F. Huang, Yu-Jen Chen, M. Hsiao, A. Wu, Zhen Yang, Y. Tzeng   +14 more
semanticscholar   +1 more source

Sesquiterpene lactone derivatives of KSL-B targeting Arf1-Big1Sec7 interaction

European Journal of Medicinal Chemistry Reports, 2022
The GDP/GTP conformational change of Arf GTPase proteins by different guanine exchange factor GEFs proteins (Big1Sec7, ARNOSec7, Brag1Sec7, etc.), modulates important eukaryotes cell functions, such as secretion, endocytosis, phagocytosis, cytokinesis ...
Sergio Ortiz, François Peurois, Euzébio Guimarães Barbosa, Mohamed Selkti, Pascale Lemoine, Jacqueline Cherfils, Raphaël Grougnet, Sabrina Boutefnouchet   +7 more
doaj  

Prospects for the use of natural terpenoids in agriculture [PDF]

BIO Web of Conferences
As a result of the conducted phytochemical studies of sesquiterpene lactones of some plants of the genus Artemisia, Centaurea, Jurinea, and Handelia of the Asteraceae family and the study of biostimulating, mutagenic, and insecticidal activity of ...
Mukhidova Zulfiya Sh., Zakirov Salakhutdin H., Khazratkulova Sevara M., Zakirova Nodira T.   +3 more
doaj   +1 more source

Tenulin 0.25-hydrate, a sesquiterpene lactone isolated from Helenium amarum

Acta Crystallographica Section E, 2013
The asymmetric unit of the title compound, C17H22O5·0.25H2O [systematic name: 2-hydroxy-2,2a,6,9a-tetramethyl-2a,4a,5,6,6a,9a,9b,9c-octahydro-2H-1,4-dioxadicyclopent[cd,f]azulene-3,9-dione 0.25-hydrate], a natural product isolated from Helenium ...
Bruce Noll, Thomas G. Waddell, Cole T. Smith, Kyle S. Knight   +3 more
doaj   +1 more source

Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.

PLoS ONE, 2013
Soft tissue sarcomas (STS) represent a rare group of malignant tumors that frequently exhibit chemotherapeutic resistance and increased metastatic potential.
Birgit Lohberger, Beate Rinner, Nicole Stuendl, Heike Kaltenegger, Bibiane Steinecker-Frohnwieser, Eva Bernhart, Ehsan Bonyadi Rad, Annelie Martina Weinberg, Andreas Leithner, Rudolf Bauer, Nadine Kretschmer   +10 more
doaj   +1 more source

Method development and validation for the extraction and quantification of sesquiterpene lactones in Dolomiaea costus

Ultrasonics Sonochemistry
Dolomiaea costus, commonly known as Indian costus, is a medicinal plant from the Asteraceae family. The root and powder of costus have been widely used to treat various health conditions.
Mohammed Aldholmi
doaj  

In Vitro Leishmanicidal Activities of Sesquiterpene Lactones from Tithonia diversifolia against Leishmania braziliensis Promastigotes and Amastigotes

Molecules, 2014
Natural compounds represent a rich and promising source of novel, biologically active chemical entities for treating leishmaniasis. Sesquiterpene lactones are a recognized class of terpenoids with a wide spectrum of biological activities, including ...
Juliano S. de Toledo, Sergio R. Ambrósio, Carly H. G. Borges, Viviane Manfrim, Daniel G. Cerri, Angela K. Cruz, Fernando B. Da Costa   +6 more
doaj   +1 more source

Microbial Transformation of the Sesquiterpene Lactone, Vulgarin, by Aspergillus niger. [PDF]

Molecules, 2023
ElGamal RA, Galala AA, Abdel-Kader MS, Badria FA, Soliman AF.   +4 more
europepmc   +1 more source