Objective. Investigation of hypolipidemic effect of sesquiterpene γ-lactone ahillin in hepatoma tissue culture (HTC) cells.Material and methods. In this study we’ve evaluated the effect of γ-lactone sesquiterpene aсhillin and gemfibrozil (comparator drug)
V. V. Ivanov +6 more
doaj +3 more sources
A sesquiterpene lactone, tomentosin, as a novel anticancer agent: orchestrating apoptosis, autophagy, and ER stress in colorectal cancer. [PDF]
Çetinkaya S +4 more
europepmc +3 more sources
The emergence of the COVID-19 pandemic declared the huge need of humanity for new and effective antiviral drugs. The reported antimicrobial activities of Artemisia sublessingiana encouraged us to investigate the ethanol extract of its aerial parts which ...
R. Jalmakhanbetova +7 more
semanticscholar +1 more source
Nanoemulsion design of
This work introduces a novel formulation strategy that advances the potential of Cynara cardunculus leaf extract enriched in sesquiterpene lactones as a bioherbicide and contributes to the broader development of sustainable weed management tools based on natural products.
Daniela W. Rosa +6 more
openalex +2 more sources
Secondary metabolites of three endemic Centaurea L. species [PDF]
The aerial parts of three endemic Centaurea L. species, namely C. tomorosii Micevski, C. soskae Hayek and C. galicicae Micevski, afforded sesquiterpene lactone cnicin (1) and seven flavonoids: apigenin (2), isokaempferide (3), hispidulin (4 ...
Tešević Vele +7 more
doaj +1 more source
Introduction: Providing fresh and healthy vegetables, produced locally and under climate-friendly conditions, is a major challenge for future agriculture.
Nikola Laurenčíková +4 more
doaj +1 more source
Carbocations and the Complex Flavor and Bouquet of Wine: Mechanistic Aspects of Terpene Biosynthesis in Wine Grapes. [PDF]
Computational chemistry approaches for studying the formation of terpenes/terpenoids in wines are presented, using five particular terpenes/terpenoids (1,8-cineole, α-ylangene, botrydial, rotundone, and the wine lactone), volatile compounds (or their ...
Pemberton, Ryan P +2 more
core +2 more sources
Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik +7 more
core +4 more sources
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo +90 more
core +1 more source
Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]
BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett +5 more
core +6 more sources

