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Antiproliferative and Pro-apoptotic Effects of Sesquiterpene Lactones from Schkuhria pinnata in THP-1 Leukemia Cells

open access: gold
Dagmar Jankovská   +8 more
openalex   +1 more source

Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ.

open access: green, 2017
Jinkui Wang   +12 more
openalex   +1 more source
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Production of Plant Sesquiterpene Lactone Parthenolide in the Yeast Cell Factory.

ACS Synthetic Biology, 2022
Parthenolide, a kind of sesquiterpene lactone, is the direct precursor for the promising anti-glioblastoma drug ACT001. Compared with traditional parthenolide source from plant extraction, de novo biosynthesis of parthenolide in microorganisms has the ...
Yi-Xiang Shi   +7 more
semanticscholar   +1 more source

Alantolactone: A sesquiterpene lactone with diverse pharmacological effects

Chemical Biology and Drug Design, 2021
Alantolactone (Ala) is a sesquiterpene lactone that can be isolated from many herbal plants belonging to Asteraceae. Besides the antimicrobial activities against bacteria, fungi and viruses, Ala has also demonstrated significant anti‐inflammatory effects
Xin Liu   +5 more
semanticscholar   +1 more source

Effect of Shading on the Sesquiterpene Lactone Content and Phytotoxicity of Cultivated Cardoon Leaf Extracts.

Journal of Agricultural and Food Chemistry, 2020
The work described here follows on from a previous study focused on the influence of the genotype and harvest time on the sesquiterpene lactone (STL) profile of Cynara cardunculus L. leaf extracts. The aim of this study was to investigate the effect that
A. Scavo   +5 more
semanticscholar   +1 more source

Sesquiterpene lactone allergy

American Journal of Contact Dermatitis, 1996
Sesquiterpene lactones are a large, diverse group of chemicals found in several plant families that cause allergic contact dermatitis. The biological, botanical, allergenic, and structural significance of sesquiterpene lactones is explored as well as the clinical characteristics of cutaneous reactions.
E M, Warshaw, K A, Zug
openaire   +2 more sources

Helenalin - A Sesquiterpene Lactone with Multidirectional Activity.

Current Drug Targets, 2019
Sesquiterpene lactones, secondary metabolites of plants, present in a large number of species mostly from the Asteracea family, are used in the traditional medicine of many countries for the treatment of various pathological conditions.
Joanna Drogosz, A. Janecka
semanticscholar   +1 more source

Influence of Genotype and Harvest Time on the Cynara cardunculus L. Sesquiterpene Lactone Profile.

Journal of Agricultural and Food Chemistry, 2019
The excessive and inappropriate application of herbicides has caused environmental pollution. The use of allelochemicals as bioherbicides could provide a solution to this problem. The allelopathic activity of Cynara cardunculus L.
A. Scavo   +5 more
semanticscholar   +1 more source

Sesquiterpene Lactones as Allelochemicals

Journal of Natural Products, 2006
Six new sesquiterpene lactones, annuolide H (3), helivypolides F, H-J (4, 11-13), and helieudesmanolide A (6), together with known compounds, were isolated from polar bioactive fractions of Helianthus annuus cv. SH-222 and Stella fresh leaf water extracts.
Macias, Francisco A.   +5 more
openaire   +3 more sources

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