Results 41 to 50 of about 97,347 (301)

Insights into the Sesquiterpenoid Pathway by Metabolic Profiling and De novo Transcriptome Assembly of Stem-Chicory (Cichorium intybus Cultigroup "Catalogna") [PDF]

, 2016
Stem-chicory of the "Catalogna" group is a vegetable consumed for bitter-flavored stems. Type and levels of bitter sesquiterpene lactones (STLs) participate in conferring bitterness in vegetables.
Alessandro Schiappa, Chiara Nicolodi, Donato Giannino, Elisabetta Di Giacomo, Gian Carlo Tenore, Giovanna Frugis, Giovanni Mele, Giulio Testone, Giuseppe Arnesi, Maria Adelaide Iannelli, Maria Gonnella, Massimiliano Renna, Massimiliano Renna   +12 more
core   +6 more sources

Preparation of an Eight-Membered Sesquiterpene Lactone Resulting from Sequential Gif System GoAggIII and MCPBA Oxidation of ( )-10β,14-Dihydroxy-allo-aromadendrane

Molecules, 2005
Studies aimed at a comparison of chemical, biomimetic (Gif system GoAggIII)and enzymatic (CHMO) transformations of natural ( )-10β,14-dihydroxy-allo-aromadendrane have led to preparation of an eight-member sesquiterpene lactone.
D. de Lima, A. Beatriz, M. Marques, M. de Bodas   +3 more
doaj   +1 more source

Isolation of a natural product with anti-mitotic activity from a toxic Canadian prairie plant

Heliyon, 2021
We are investigating plants from the prairie ecological zone of Canada to identify natural products that inhibit mitosis in cancer cells. Investigation of plant parts from the Canadian plant species Hymenoxys richardsonii (Asteraceae) revealed that leaf ...
Layla Molina, David E. Williams, Raymond J. Andersen, Roy M. Golsteyn   +3 more
doaj   +1 more source

Purpurolide A, 5/5/5 Spirocyclic Sesquiterpene Lactone in Nature from the Endophytic Fungus Penicillium purpurogenum.

Organic Letters, 2018
Purpurolide A (1), an unprecedent sesquiterpene lactone with a rarely encountered 5/5/5 spirocyclic skeleton, along with two new 6/4/5/5 tetracyclic sesquiterpene lactones (2 and 3), were isolated from the cultures of the endophytic fungus Penicillium ...
Yanan Wang, Guiyang Xia, Lingyan Wang, Guangbo Ge, Huawei Zhang, Jing-Fang Zhang, Yuzhuo Wu, Sheng Lin   +7 more
semanticscholar   +1 more source

Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana [PDF]

, 2013
Leishmaniasis is a worldwide parasitic disease, caused by monoflagellate parasites of the genus Leishmania. In the search for more effective agents against these parasites, the identification of molecular targets has been attempted to ensure the ...
Barrera, Patricia Andrea, Beer, Maria Florencia, Lozano, Esteban Sebastián, Martino, Virginia Susana, Rivera, Monica Raquel, Sosa Escudero, Miguel Angel, Sülsen, Valeria Patricia, Tonn, Carlos Eugenio   +7 more
core   +3 more sources

The plant sesquiterpene lactone parthenolide inhibits Wnt/β-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1

Journal of Biological Chemistry, 2018
The Wnt/β-catenin pathway is essential for embryonic development and homeostasis, but excessive activation of this pathway is frequently observed in various human diseases, including cancer.
Xiaoliang Zhu, Chunmao Yuan, Chenyang Tian, Chen Li, Fen Nie, Xiaomin Song, Rong Zeng, Dianqing Wu, X. Hao, Lin Li   +9 more
semanticscholar   +1 more source

Plant sesquiterpene lactones

Philosophical Transactions of the Royal Society B: Biological Sciences
Sesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the evolutionary and ecological significance of STLs, highlighting their roles in plant defence mechanisms against herbivory and as ...
Olivia Agatha, Daniela Mutwil-Anderwald, Jhing Yein Tan, Marek Mutwil   +3 more
openaire   +4 more sources

Synthesis and conformational analysis of leptocarpin derivatives. Influence of modification of the oxirane ringon leptocarpin's cytotoxic activity. [PDF]

, 2006
Indexación: ScieloABSTRACT The reaction in acidconditions of Leptocarpin 1, a compound with antitumor activity, formed two new isomeric products, 8b-angeloyl-1b,3b-dihydroxy-4,10-dimethyl,-D11(13) methylen-4Z,9Z-dieneheliangol-6,12-olide 2 and 8b ...
...[et al.]., Carracso, Héctor, Kesternich, Victor, Martínez, Rolando, Álvarez-Contreras, Carolina   +4 more
core   +1 more source

Targeted Screening and Quantification of Characteristic Sesquiterpene Lactones in Ambrosia artemisiifolia L. at Different Growth Stages

Plants
Sesquiterpene lactones are specialized plant metabolites with promising pharmacological activities. These metabolites are characteristic marker compounds for the aerial parts of Ambrosia artemisiifolia.
Balázs Kovács, Péter Püski, Ákos Bajtel, Elek Ferencz, Boglárka Csupor-Löffler, Dezső Csupor, Tivadar Kiss   +6 more
doaj   +1 more source

Root constituents of Lactuca sibirica and a comparison of metabolite profiles of L. sibirica and L. tatarica

Acta Societatis Botanicorum Poloniae, 2011
Nine known sesquiterpene lactones, including four lactucin-type guaianolides, four costuslactone-type guaianolides and one germacranolide, were isolated from roots of Lactuca sibirica (Asteraceae), six of which were glycoside derivatives.
Wanda Kisiel, Klaudia Michalska
doaj   +1 more source