Results 81 to 90 of about 97,347 (301)
Cellular differentiation is pivotal in health and disease. Interfering with the process of differentiation, such as inhibiting the differentiation of adipocytes and inducing the differentiation of cancer cells, is considered a therapeutic approach ...
Sepand Tehrani Fateh +7 more
doaj +1 more source
Sesquiterpenoids in subtribe Centaureinae (Cass.) Dumort (tribe Cardueae, Asteraceae): distribution, 13C-NMR spectral data and biological properties [PDF]
Asteraceae Bercht. & J. Presl is one of the biggest and most economically important plant families. The taxonomy and phylogeny of Asteraceae is rather complex and according to the latest and most reliable taxonomic classification of Panero & Funk, based ...
Bancheva, S. +3 more
core +1 more source
Heteroatom-Containing Natural Sesquiterpene Lactones and Methods for their Obtaining
This review shows the data about isolated heteroatom-containing sesquiterpene lactones from various genera of Asteraceae family, natural occurence, isolation methods and their biological activity.
S. M. Adekenov, G. A. Atazhanova
doaj +1 more source
Expanding the Study of the Cytotoxicity of Incomptines A and B against Leukemia Cells
Heliangolide-type sesquiterpene lactones (HTSLs) are phytocompounds with several pharmacological activities including cytotoxic and antitumor activity. Both bioactivities are related to an α-methylene-γ-lactone moiety and an ester group on carbon C-8 in ...
Fernando Calzada +6 more
doaj +1 more source
Pancreatic cancer is aggressive and therefore difficult to treat; however, continued efforts have been made with the aim of developing an effective therapy against the disease.
H. Lee +5 more
semanticscholar +1 more source
In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver [PDF]
Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the ...
Ekstrand, Bo +2 more
core +1 more source
Contact Sensitization in Adults With Atopic Dermatitis: A 21‐Year Single‐Center Tertiary Experience
A graphical abstract has been included as supplemental material. ABSTRACT Background Atopic dermatitis is a common chronic inflammatory skin condition. Data on contact sensitization in adults with atopic dermatitis remain limited. Objectives To investigate the prevalence of contact sensitization in adults with and without AD: Patients/Methods A ...
Francesca Caroppo +5 more
wiley +1 more source
Invasive and non-invasive congeneric Centaurea (Asteraceae) show contrasting patterns of herbivory by snails [PDF]
Background and aims – Once introduced into new regions, exotic species often experience shifts in resource allocation in response to the different environmental conditions found in the introduction range. Plants naturally respond to specialist herbivores
Eren, Ozkan +5 more
core +2 more sources
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen +7 more
wiley +1 more source
Guaianolide Sesquiterpene Lactones from Centaurothamnus maximus [PDF]
Taha A. Hussien +6 more
openalex +1 more source

