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Sesquiterpene Lactones Revisited
1995Sesquiterpene lactones are plant constituents often possessing a bitter taste which are common in most tribes of the Asteraceae (Compositae) and also are found in at least 14 other angiosperm families and to a limited extend in gymnosperms, liverworts and fungi.1 There are more than 4,000 known structures in this class of plant secondary metabolites ...
Robin J. Maries +5 more
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The first sesquiterpene lactones esterified with a sesquiterpenic acid
Phytochemistry, 1981Abstract From Hypochoeris glabra two guaianolides esterified with an unusual sesquiterpenic acid were isolated. Proton-catalysed rearrangement of the cyclopropane derivative led to a phenolic acid. The structures were elucidated by high-field 1 H NMR spectroscopy. Further guaianolides were isolated from H. uniflora and Lactuca floridana . These
Ferdinand Bohlmann +3 more
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Sesquiterpene lactones from Achillea crithmifolia
Phytochemistry, 1991Abstract The isolation of guaianolides rupicolin-A, rupicolin-B, their acetates and a new germacranolide 1β,10α-epoxy-3β,9β-diacetoxy-11α,13-dihydrocostunolide, identified by means of PS DQF COSY and PS NOESY, from Achillea crithmifolia is reported. A flavonoid jaceidin was also isolated from the same extract.
Milosavljević, Slobodan +4 more
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Sesquiterpene lactones from Anthemis plutonia
Phytochemistry, 1998Aerial parts of Anthemis plutonia furnished three guaianolides, one of them new.
Maurizio, Bruno +4 more
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Sesquiterpene lactones from Saussurea involucrata
Fitoterapia, 2011Bioassay-directed separation of the ethyl acetate extract from the aerial parts of Saussurea involucrata (Kar. et Kir. ex Maxim) led to the isolation of three new sesquiterpene lactones sausinlactones A (1), B (2), C (3) and six known ones (4-9). The structures were established by spectroscopic data (UV, IR, HRESIMS, 1D and 2D NMR).
Wan, Xiao +6 more
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Alkylation of deoxyguanosine by the sesquiterpene lactone hymenoxon
Toxicology Letters, 1985Hymenoxon, a toxic sesquiterpene lactone found in the ruminant forage plant Hymenoxys odorata, binds deoxyguanosine in a cell-free system, and forms adducted guanine residues in sheep lymphocyte DNA. Mitogen-stimulated DNA synthesis in lymphocytes was inhibited by hymenoxon at concentrations greater than 100 microM.
Sylvia, VL +4 more
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Sesquiterpene Lactones in Compositae
1971The degree to which modern techniques of chemical analysis and structure determi1nation have contributed to the development of our knowledge of plant constituents is aptly illustrated by considering recent developments in sesquiterpene chemistry. Comparison of the relatively small sesquiterpene section in Simonsen’s classic treatise1) with the ever ...
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Contact Dermatitis Caused by Sesquiterpene Lactones
American Journal of Contact Dermatitis, 1998Compositae dermatitis involves workers such as gardeners, florists, and farmers, and less commonly people not employed in occupations at risk.To report a case of contact sensitization caused by Compositae, the source of sensitization being both pesticides and plants.A 65-year-old man, whose hobby was gardening, was affected by a chronic eczema of the ...
E, Spettoli +4 more
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Allergenic Component of a Liverwort: A Sesquiterpene Lactone
Science, 1969Frullania spp. (Hepaticae, Jungermanniales) are agents of allergies. Extraction and fractionation of Frullania tamarisci has given, as the only allergenic component isolated, a levorotatory crystalline substance, the structure of which is demonstrated. It is a sesquiterpene lactone.
H, Knoche +4 more
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Advances in sesquiterpene lactones extraction
TrAC Trends in Analytical Chemistry, 2022Teresa Brás +3 more
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