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Chemistry of Sesquiterpene Lactones
2018Sesquiterpene lactones are a class of bioactive plant products that display an array of biological and pharmacological activities such as antimicrobial, cytotoxic, anti-inflammatory, antiviral, antibacterial, and antifungal. A vast amount of sesquiterpene molecular structures has been reported, and the largest numbers of these types of compounds can be
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Perspectives on Sesquiterpene Lactones in Inflammation and Cancer
Current Drug Targets, 2011Sesquiterpene lactones are a large group of secondary plant metabolites mostly known from the Asteraceae family. They exert a broad variety of different biological activities. This review attempts to critically summarise the knowledge on the anti-inflammatory and cytotoxic activity of SLs, with a special focus on parthenolide and helenalin.
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Paucin, a sesquiterpene lactone glucoside
Tetrahedron Letters, 1969T G, Waddell, T A, Geissman
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Sesquiterpene lactones of Eupatorium perfoliatum
The Journal of Organic Chemistry, 1977Werner Herz +3 more
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Toxicity of sesquiterpene lactones.
Research communications in chemical pathology and pharmacology, 1980The intraperitoneal LD50 of 7 sesquiterpene lactones were determined (in mg/kg): mexicanin-E (3, 3.08 +/- .10), helenalin (1, 9.86 +/- .08), hymenoxon (2, 16.24 +/- .10), psilotropin (4, 112.25 +/- .17), hymenoxon dimethyl ether (5, 141.42 +/- 0), tenulin (6, 184.65 +/- .06), and hymenolane (7, above 200).
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