Results 31 to 40 of about 16,757 (265)

Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]

, 2019
BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett, Dhanota, Puja, Fiehn, Oliver, Karunanithi, Prema S, Tong, Shen, Zerbe, Philipp   +5 more
core   +6 more sources

CRISPR/Cas9 targeted inactivation of the kauniolide synthase in chicory results in accumulation of costunolide and its conjugates in taproots

Frontiers in Plant Science, 2022
Chicory taproots accumulate sesquiterpene lactones lactucin, lactucopicrin, and 8-deoxylactucin, predominantly in their oxalated forms. The biosynthetic pathway for chicory sesquiterpene lactones has only partly been elucidated; the enzymes that convert ...
Katarina Cankar, Johanna Christina Hakkert, Robert Sevenier, Eva Campo, Bert Schipper, Christina Papastolopoulou, Khabat Vahabi, Alain Tissier, Paul Bundock, Dirk Bosch   +9 more
doaj   +1 more source

Technological methods of sesquiterpene lactones extraction from raw materials

Eurasian Chemico-Technological Journal, 2009
Methods of sesquiterpene lactones extraction used in pharmaceutical manufacture have been summarized. The alternative method of extraction and purification of sesquiterpene lactones of arglabin and leucomisin has been offered.
I. A. Khabarov
doaj   +1 more source

Oviposition inhibitory activity of the Mexican sunflower Tithonia diversifolia (Asteraceae) polar extracts against the two-spotted spider mite Tetranychus urticae (Tetranychidae) [PDF]

, 2018
The Mexican sunflower (Tithonia diversifolia, Asteraceae) is an invasive shrub of agricultural and non-agricultural lands in tropical countries. Besides extensive utilizations in the traditional medicine, mainly to treat malaria, the plant is believed to
Baldan, Valeria, Benelli, Giovanni, Biapa Nya, Prosper C., Canale, Angelo, Cappellacci, Loredana, Dall'Acqua, Stefano, Maggi, Filippo, Ngahang Kamte, Stephane L., Nicoletti, Marcello, Pavela, Roman, Petrelli, Riccardo, Sut, Stefania   +11 more
core   +1 more source

Yield and Chemical Composition of Raw Material from Meadow Arnica (Arnica chamissonis Less.) Depending on Soil Conditions and Nitrogen Fertilization

Agriculture, 2021
Considering the global tendency towards using valuable secondary metabolites of plant origin, there is a need to optimize the cultivation of herbal plants, e.g., the meadow arnica (A. chamissonis Less.).
Katarzyna Olesińska, Danuta Sugier, Zdzisław Kaczmarski   +2 more
doaj   +1 more source

Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana [PDF]

, 2013
Leishmaniasis is a worldwide parasitic disease, caused by monoflagellate parasites of the genus Leishmania. In the search for more effective agents against these parasites, the identification of molecular targets has been attempted to ensure the ...
Barrera, Patricia Andrea, Beer, Maria Florencia, Lozano, Esteban Sebastián, Martino, Virginia Susana, Rivera, Monica Raquel, Sosa Escudero, Miguel Angel, Sülsen, Valeria Patricia, Tonn, Carlos Eugenio   +7 more
core   +3 more sources

Natural Sesquiterpene Lactones as Renewable Chemical Materials for New Medicinal Products

Eurasian Chemico-Technological Journal, 2013
Literature data and own research results on the technology for isolating natural sesquiterpene lactones such as arglabin, alantolactone, artemisinin, grosheimin, isoalantolactone, parthenolide, santonin and potential possibilities of their use as ...
S. M. Adekenov
doaj   +1 more source

Feature-Based Molecular Networking for the Exploration of the Metabolome Diversity of Common Egyptian Centaurea Species in Relation to Their Cytotoxic Activity

Molecules, 2023
Centaurea is a genus compromising over 250 herbaceous flowering species and is used traditionally to treat several ailments. Among the Egyptian Centaurea species, C. lipii was reported to be cytotoxic against multidrug-resistant cancer cells.
Eman H. Reda, Nesrine M. Hegazi, Mona Marzouk, Zienab T. Abdel Shakour, Ali M. El-Halawany, El-Sayeda A. El-Kashoury, Tarik A. Mohamed, Mahmoud A. A. Ibrahim, Khaled A. Shams, Nahla S. Abdel-Azim, Christopher J. Kampf, Thomas Efferth, Paul. W. Paré, Mohamed-Elamir F. Hegazy   +13 more
doaj   +1 more source

Perception of bitterness, sweetness and liking of different genotypes of lettuce [PDF]

, 2016
Lettuce is an important leafy vegetable, consumed across the world, containing bitter sesquiterpenoid lactone (SL) compounds that may negatively affect consumer acceptance and consumption.
Chadwick, Martin, Gawthrop, Frances, Methven, Lisa, Michelmore, Richard W., Wagstaff, Carol   +4 more
core   +1 more source

Insights into the Sesquiterpenoid Pathway by Metabolic Profiling and De novo Transcriptome Assembly of Stem-Chicory (Cichorium intybus Cultigroup "Catalogna") [PDF]

, 2016
Stem-chicory of the "Catalogna" group is a vegetable consumed for bitter-flavored stems. Type and levels of bitter sesquiterpene lactones (STLs) participate in conferring bitterness in vegetables.
Alessandro Schiappa, Chiara Nicolodi, Donato Giannino, Elisabetta Di Giacomo, Gian Carlo Tenore, Giovanna Frugis, Giovanni Mele, Giulio Testone, Giuseppe Arnesi, Maria Adelaide Iannelli, Maria Gonnella, Massimiliano Renna, Massimiliano Renna   +12 more
core   +2 more sources