Results 41 to 50 of about 14,482 (229)

In situ and in vitro comparative study on the bioproductivity of Arnicae folium et caulis from the northern area of the Romanian eastern carpathians [PDF]

, 2014
Arnica montana L. is an important plant bioresource, being traditionally used as medicinal plant, for which the scientific and economic interest remains at a high level.
Dănilă, Doina, Tănase, Cătălin, Wolfram, Evelyn, Ştefanache, Camelia Paula   +3 more
core   +2 more sources

In vitro antimicrobial activity of total sesquiterpene lactones and phenols isolated from some Iraqi plants

مجلة بغداد للعلوم, 2008
The antimicrobial potency of the crude ethanolic extracts from different Iraqi plants were evaluated . Further more, total sesquiterpene lactones and phenolic compounds were isolated and their antimicrobial activity attempted.
Baghdad Science Journal
doaj   +1 more source

Transcriptome analysis of Thapsia laciniata rouy provides insights into terpenoid biosynthesis and diversity in apiaceae [PDF]

, 2013
Thapsia laciniata Rouy (Apiaceae) produces irregular and regular sesquiterpenoids with thapsane and guaiene carbon skeletons, as found in other Apiaceae species.
Acquadro, Avato, Bak, Bjørn Dueholm, Bouvier, Cavagnaro, Christensen, Christoph Sensen, Cool, Corinna Weitzel, Damian Drew, De Kraker, Drew, Drew, Eddy, Gaasterland, Guindon, Hegnauer, Hemmerlin, Henrik Simonsen, Holub, Ikezawa, Iorizzo, Kotchoni, Mao, Martin, Meisel, Moriya, Nelson, Nguyen, Nørholm, Ogata, Pickel, Polichuk, Ro, Rouy, Rubal, Ruhlman, Schulz, Simonsen, Smitt, Sui, Tang, Teoh, Tholl, Thulasiram, Tutin, Weitzel, Ye Zhang, Yu, Zerbino   +50 more
core   +2 more sources

Pretraživanje tradicionalnih europskih ljekovitih biljaka na inhibiciju acetilkolinesteraze i butirilkolinesteraze [PDF]

, 2010
Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of Alzheimer’s disease (AD) to enhance central cholinergic transmission. On the other hand, butyrylcholinesterase (BuChE) inhibitors were reported to produce significant
A. Adsersen, A. Ferreira, A. Marston, Agnieszka Kuciun, Anna Kiss, E. Teuscher, G. Ellman, G. Romussi, H. Wolf, M. Wichtl, N. Perry, Natalia Wszelaki, P. Bradley, R. Houghton, R. Lane, S. Kang, T. Mennini   +16 more
core   +3 more sources

Cytotoxicity of the Sesquiterpene Lactones, Ivalin and Parthenolide in Murine Muscle Cell Lines and Their Effect on Desmin, a Cytoskeletal Intermediate Filament

Toxins, 2020
Vermeersiekte or “vomiting disease” is an economically important disease of ruminants following ingestion of Geigeria (G.) species in South Africa. Sheep are more susceptible, and poisoning is characterized by stiffness, regurgitation, bloat, paresis ...
Christo J. Botha, Y. Zethu Mathe, Gezina C. H. Ferreira, E. Annette Venter   +3 more
doaj   +1 more source

Cytotoxic sesquiterpene lactones from the aerial parts of Inula aucheriana.

Anais da Academia Brasileira de Ciências, 2015
Inula aucheriana DC is a member of the family Asteraceae which is known to produce cytotoxic secondary metabolites noted as sesquiterpene lactones. In the present study, sesquiterpene lactones inuchinenolide B, 6-deoxychamissonolide (stevin) and 14 ...
Ahmad Reza Gohari, Mahmoud Mosaddegh, Farzaneh Naghibi, Bahara Eslami-Tehrani, Atefeh Pirani, Maryam Hamzeloo-Moghadam, Roger W. Read   +6 more
doaj   +1 more source

A metabolomic approach to target compounds from the asteraceae family for dual COX and LOX inhibition [PDF]

, 2015
The application of metabolomics in phytochemical analysis is an innovative strategy for targeting active compounds from a complex plant extract. Species of the Asteraceae family are well-known to exhibit potent anti-inflammatory (AI) activity.
Chagas-Paula, Daniela A., Da Costa, Fernando B., Edrada-Ebel, RuAngelie, Zhang, Tong   +3 more
core   +2 more sources

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Phytochemical Profile, Mineral Content, and Bioactive Compounds in Leaves of Seed-Propagated Artichoke Hybrid Cultivars

Molecules, 2020
The globe artichoke (Cynara cardunculus L. subsp. Scolymus (L.) Hegi) is a multi-year species rich in various classes of phytochemicals with known nutritional and pharmacological properties, such as polyphenols, sesquiterpene lactones, and terpenoids ...
Gabriele Rocchetti, Luigi Lucini, Giandomenico Corrado, Giuseppe Colla, Mariateresa Cardarelli, Stefania De Pascale, Youssef Rouphael   +6 more
doaj   +1 more source

Trypanocidal Activity of Smallanthus sonchifolius. Identification of Active Sesquiterpene Lactones by Bioassay-Guided Fractionation. [PDF]

, 2013
In order to find novel plant-derived biologically active compounds against Trypanosoma cruzi, we isolated, from the organic extract of Smallanthus sonchifolius, the sesquiterpene lactones enhydrin (1), uvedalin (2), and polymatin B (3) by bioassay-guided
Catalan, Cesar Atilio Nazareno, Cazorla, Silvia Ines, Frank, Fernanda Maria, Grau, A., Malchiodi, Emilio Luis, Maravilla, G., Martino, Virginia Susana, Muschietti, Liliana, Ulloa, Jerónimo Luis   +8 more
core   +4 more sources