Results 41 to 50 of about 105,849 (264)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Set-valued convex compositions
, 2023 We study the composition of two set-valued functions defined on locally convex topological linear spaces. We assume that these functions map into certain complete lattices of sets that have been used to establish a conjugation theory for set-valued ...
Ararat, Çağın
core
Strict Efficiency in Vector Optimization with Nearly Convexlike Set-Valued Maps
Abstract and Applied Analysis, 2013 The concept of the well posedness for a special scalar problem is linked with strictly efficient solutions of vector optimization problem involving nearly convexlike set-valued maps.
Xiaohong Hu, Zhimiao Fang, Yunxuan Xiong
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Stability Analysis for Higher-Order Adjacent Derivative in Parametrized Vector Optimization
Journal of Inequalities and Applications, 2010 By virtue of higher-order adjacent derivative of set-valued maps, relationships between higher-order adjacent derivative of a set-valued map and its profile map are discussed.
Sun XK, Li SJ
doaj
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Kind of New Higher-Order Mond-Weir Type Duality for Set-Valued Optimization Problems
Mathematics, 2019 In this paper, we introduce the notion of higher-order weak adjacent epiderivative for a set-valued map without lower-order approximating directions and obtain existence theorem and some properties of the epiderivative.
Liu He +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Second-Order Contingent Derivative of the Perturbation Map in Multiobjective Optimization
Fixed Point Theory and Applications, 2011 Some relationships between the second-order contingent derivative of a set-valued map and its profile map are obtained. By virtue of the second-order contingent derivatives of set-valued maps, some results concerning sensitivity analysis are obtained in
Li SJ, Wang QL
doaj