Results 51 to 60 of about 105,849 (264)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Lesser Sunda Islands 1:250,000 /

open access: yes, 1943
Various editions. Topographic map series of Lesser Sunda Islands, Indonesia. Five classes of roads and trails, various types of air fields, and two types of internal boundaries are shown.; Elevations are shown by hachures or contours, and spot heights ...
United States. Army Map Service, cartographer.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Weak Sharp Minima in Set-Valued Optimization Problems

open access: yesAbstract and Applied Analysis, 2012
We introduce the notion of a weak ψ-sharp minimizer for set-valued optimization problems. We present some sufficient and necessary conditions that a pair point is a weak ψ-sharp minimizer through the outer limit of set-valued map and develop the ...
Ming-hao Jin, Jun-xiang Wang, Shu Xu
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Continuous and Lipschitzian Selections from a Measurable Set-Valued Map

open access: yes, 1992
this paper we construct for a given measurable set-valued map K : (0; T ) ;
Ivo Vrkoc, Vlastimil Krivan
core  

Set-Valued Interpolative Hardy–Rogers and Set-Valued Reich–Rus–Ćirić-Type Contractions in b-Metric Spaces

open access: yesMathematics, 2019
In this paper, using an interpolative approach, we investigate two fixed point theorems in the framework of a b-metric space whose all closed and bounded subsets are compact. One of the theorems is for set-valued Hardy−Rogers-type and the other one
Pradip Debnath, Manuel de La Sen
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Western Siberia 1:250,000 [cartographic material].

open access: yes, 1954
Issued in quadrangles of 1° of latitude by 2-3° of longitude. Set includes various issues of some sheets.; Relief indicated variously by contours, form lines, shading, and spot heights.; Coordinated with series N501, Eastern Europe and N503, Central ...
United States. Army Map Service.
core  

The study of higher-order resonant and non-resonant boundary value problems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
The existence of at least one solution to a nonlinear $n^\textrm{th}$ order differential equation $x^{(n)} = f(t,x,x',\ldots,x^{(n-1)}), \ 0
Aijun Yang   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy