Results 111 to 120 of about 1,627,856 (332)
The Inverse Problem for Perturbed Harmonic Oscillator on the Half-Line with a Dirichlet Boundary Condition [PDF]
.: We consider the perturbed harmonic oscillator $$T_{D}\psi=-\psi^{\prime\prime}+x^{2}\psi+q(x)\psi, \psi(0)=0,$$ in $$L^{2}(\mathbb{R}_{+})$$ , where $$q \in {\mathbf{H}}_{+} = \{q^{\prime}, xq \in L^{2}(\mathbb{R}_{+})\}$$ is a real-valued potential ...
Chelkak, Dmitry, Korotyaev, Evgeny
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Accelerated method of finding for the minimum of arbitrary Lipschitz convex function
The goal of the paper is development of an optimization method with the superlinear convergence rate for an arbitrary convex function. For optimization an approximation is used that is similar to the Steklov integral averaging.
Prudnikov, I. M.
core
The author presents several definitions of convex and quasiconvex set-valued maps and gives some relationships between them.
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Single-valued representation of set-valued mappings [PDF]
It is shown that the graph of a set-valued mapping satisfying typical conditions which guarantee the existence of measurable selections can be represented as the union of graphs of measurable single-valued mappings depending continuously on a parameter running through some Polish space.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Existence of viable solutions for nonconvex differential inclusions
We show the existence result of viable solutions to the differential inclusion $$displaylines{ dot x(t)in G(x(t))+F(t,x(t)) cr x(t)in S quad hbox{on } [0,T], }$$ where $F: [0,T]imes Ho H$ $(T>0)$ is a continuous set-valued mapping, $G ...
Messaoud Bounkhel, Tahar Haddad
doaj
Generalized quasiconvex set-valued maps
The aim of this paper is to introduce a concept of quasiconvexity for set-valued maps in a general framework, by only considering an abstract convexity structure in the domain and an arbitrary binary relation in the codomain. It is shown that this concept can be characterized in terms of usual quasiconvexity of certain real-valued functions.
openaire +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

