Results 91 to 100 of about 152,676 (293)
Optimality conditions in set-valued optimization using approximations as generalized derivatives
, 2022 The set criterion is an appropriate defining approach regarding the solutions for the set-valued optimization problems. By using approximations as generalized derivatives of set-valued mappings, we establish necessary optimality conditions for a ...
Ichatouhane, Aissam +1 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Weak Clarke epiderivative in set-valued optimization
, 2008 A new notion of weak Clarke epiderivative for a set-valued map is introduced using the concept of Clarke tangent cone. The existence, characterization and properties of weak Clarke epiderivative are then studied.
Arora, R., Lalitha, C.S.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A recursive algorithm for multivariate risk measures and a set-valued Bellman's principle
, 2016 A method for calculating multi-portfolio time consistent multivariate risk measures in discrete time is presented. Market models for $d$ assets with transaction costs or illiquidity and possible trading constraints are considered on a finite probability ...
Rudloff, Birgit, Feinstein, Zachary
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Stability Analysis for Higher-Order Adjacent Derivative in Parametrized Vector Optimization
Journal of Inequalities and Applications, 2010 By virtue of higher-order adjacent derivative of set-valued maps, relationships between higher-order adjacent derivative of a set-valued map and its profile map are discussed.
Sun XK, Li SJ
doaj
Complex-valued symmetric radial basis function network for beamforming
, 2009 The complex-valued radial basis function (RBF) network proposed by Chen et al. (1994) has found many applications for processing complex-valued signals, in particular, for communication channel equalization and signal detection.
Sheng Chen, Chen, Sheng
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source