Results 81 to 90 of about 152,676 (293)

New Approximate Schemes for Generalized General Set-Valued Mixed Quasi Variational Inequalities

open access: yes, 2008
In this paper, we suggest and consider a class of new three-step approximation schemes for generalized general set-valued mixed quasi variational inequalities.
Shi, Chaofeng
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tightly Proper Efficiency in Vector Optimization with Nearly Cone-Subconvexlike Set-Valued Maps

open access: yesJournal of Inequalities and Applications, 2011
A scalarization theorem and two Lagrange multiplier theorems are established for tightly proper efficiency in vector optimization involving nearly cone-subconvexlike set-valued maps.
Xu YD, Li SJ
doaj   +2 more sources

A Kind of New Higher-Order Mond-Weir Type Duality for Set-Valued Optimization Problems

open access: yesMathematics, 2019
In this paper, we introduce the notion of higher-order weak adjacent epiderivative for a set-valued map without lower-order approximating directions and obtain existence theorem and some properties of the epiderivative.
Liu He   +4 more
doaj   +1 more source

Well-posedness and scalarization in vector optimization [PDF]

open access: yes
In this paper we study several existing notions of well-posedness for vector optimization problems. We distinguish them into two classes and we establish the hierarchical structure of their relationships.
Rocca Matteo   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Well-posed Vector Optimization Problems and Vector Variational Inequalities [PDF]

open access: yes
In this paper we introduce notions of well-posedness for a vector optimization problem and for a vector variational inequality of differential type, we study their basic properties and we establish the links among them.
Rocca Matteo
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Scalarization of Set-Valued Optimization Problems in Normed Spaces

open access: yes, 2015
This work focuses on scalarization processes for nonconvex set-valued optimization problems whose solutions are defined by the socalled l-type less order relation, the final space is normed and the ordering cone is not necessarily solid.
Jiménez, Bienvenido   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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