Results 61 to 70 of about 152,676 (293)

Prederivatives of gamma paraconvex set-valued maps and Pareto optimality conditions for set optimization problems

open access: yesJournal of Inequalities and Applications, 2017
Prederivatives play an important role in the research of set optimization problems. First, we establish several existence theorems of prederivatives for γ-paraconvex set-valued mappings in Banach spaces with γ > 0 $\gamma>0$ .
Hui Huang, Jixian Ning
doaj   +1 more source

Unified optimality conditions for set-valued optimizations

open access: yesJournal of Industrial and Management Optimization, 2019
This paper is devoted to the study of unified optimality conditions for constrained set-valued optimization problems via image space analysis. Necessary and sufficient optimality conditions are given in terms of tangent cones of extended image set.
Geng-Hua Li, Sheng-Jie Li
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Higher-Order Weakly Generalized Epiderivatives and Applications to Optimality Conditions

open access: yesJournal of Applied Mathematics, 2012
The notions of higher-order weakly generalized contingent epiderivative and higher-order weakly generalized adjacent epiderivative for set-valued maps are proposed.
Qilin Wang, Guolin Yu
doaj   +1 more source

Fixed points of set-valued maps in locally complete spaces

open access: yesFixed Point Theory and Applications, 2017
We prove an extension of the Pareto optimization criterion to locally complete locally convex vector spaces to guarantee the existence of fixed points of set-valued maps.
Carlos Bosch   +4 more
doaj   +1 more source

On constrained set-valued optimization [PDF]

open access: yes
The set-valued optimization problem minC F(x), G(x)\(-K) 6= ; is considered, where F : Rn Rm and G : Rn Rp are set-valued functions, and C Rm and K Rp are closed convex cones.
Rocca Matteo, Ginchev Ivan
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

One Optimization Problem with Convex Set-Valued Mapping and Duality

open access: yesAxioms
This study focuses on the formulation and analysis of problems that are dual to those defined by convex set-valued mappings. Various important classes of optimization problems—such as the classical problems of mathematical and linear programming, as well
Elimhan N. Mahmudov, Uğur Yıldırım
doaj   +1 more source

Second-Order Optimality Conditions for Set-Valued Optimization Problems Under Benson Proper Efficiency

open access: yesAbstract and Applied Analysis, 2011
Some new properties are obtained for generalized second-order contingent (adjacent) epiderivatives of set-valued maps. By employing the generalized second-order adjacent epiderivatives, necessary and sufficient conditions of Benson proper efficient ...
Qilin Wang, Guolin Yu
doaj   +1 more source

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