Results 51 to 60 of about 1,171,805 (264)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

The myelin water imaging transcriptome: myelin water fraction regionally varies with oligodendrocyte-specific gene expression

Molecular Brain
Identifying sensitive and specific measures that can quantify myelin are instrumental in characterizing microstructural changes in neurological conditions. Neuroimaging transcriptomics is emerging as a valuable technique in this regard, offering insights
Jaimie J. Lee, Paulina S. Scheuren, Hanwen Liu, Ryan W. J. Loke, Cornelia Laule, Catrina M. Loucks, John L.K. Kramer   +6 more
doaj   +1 more source

Rainfall–runoff modelling using Long Short-Term Memory (LSTM) networks

Hydrology and Earth System Sciences, 2018
. Rainfall–runoff modelling is one of the key challenges in the field of hydrology. Various approaches exist, ranging from physically based over conceptual to fully data-driven models.
Frederik Kratzert, D. Klotz, Claire Brenner, K. Schulz, M. Herrnegger   +4 more
semanticscholar   +1 more source

Triangular Fuzzy-Rough Set Based Fuzzification of Fuzzy Rule-Based Systems

Journal of Artificial Intelligence and Soft Computing Research, 2020
In real-world approximation problems, precise input data are economically expensive. Therefore, fuzzy methods devoted to uncertain data are in the focus of current research.
Janusz T. Starczewski, P. Goetzen, Christian Napoli   +2 more
semanticscholar   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Rationally Design Thermoelectric Materials Based on Ingenious Machine Learning Methods

Advanced Electronic Materials
Data quality, feature interpretability, and model generalization are critical and challenging for applying machine learning (ML) in the design of high‐efficiency materials.
Yuqing Sun, Xiaorui Chen, Jianzhi Gao, Wenliang Zhu, Minghu Pan   +4 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Updated world map of the Köppen-Geiger climate classification

, 2007
. Although now over 100 years old, the classification of climate originally formulated by Wladimir Koppen and modified by his collaborators and successors, is still in widespread use.
M. Peel, B. Finlayson, T. McMahon
semanticscholar   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Epigenetics & Chromatin, 2021
Background Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease.
Michael Scherer, Gilles Gasparoni, Souad Rahmouni, Tatiana Shashkova, Marion Arnoux, Edouard Louis, Arina Nostaeva, Diana Avalos, Emmanouil T. Dermitzakis, Yurii S. Aulchenko, Thomas Lengauer, Paul A. Lyons, Michel Georges, Jörn Walter   +13 more
doaj   +1 more source