Results 91 to 100 of about 1,007,209 (285)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Local Aggregation in a Dynamic Setting [PDF]
Although it is not possible, in general, to give a macro description of a micro model over the entire state space of the micro model, it is possible to aggregate exactly over a subspace.
Schlicht, Ekkehart
core +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Generalized Gaussian wave packet dynamics: Integrable and Chaotic Systems
, 2016 The ultimate semiclassical wave packet propagation technique is a complex, time-dependent WBK method known as generalized Gaussian wave packet dynamics (GGWPD).
Pal, Harinder +2 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Analysis and simulation of rare events for SPDEs*
ESAIM: Proceedings and Surveys, 2015 In this work, we consider the numerical estimation of the probability for a stochastic process to hit a set B before reaching another set A. This event is assumed to be rare.
Bréhier Charles-Edouard +3 more
doaj +1 more source
Principle of territoriality: trajectories and settings
, 2016 Starting from the concepts of principle and territory, this article presents the historical marks and settings of the Principle of Territoriality on archival approach. Starts of a master's research, analyzes the importance of the principle for the development of Archival Science as a scientific discipline, through the analysis of 35 textbooks from the ...
Corrêa, Fernando Gabriel +1 more
openaire +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Optimisation of Low-Thrust and Hybrid Earth-Moon Transfers [PDF]
, 2016 This paper presents an optimization procedure to generate fast and low-∆v Earth-Moon transfer trajectories, by exploiting the multi-body dynamics of the Sun-Earth-Moon system.
Ceriotti, Matteo +3 more
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