Results 111 to 120 of about 449,899 (310)
The archaeology of early settlement in upper Teesdale, co. Durham [PDF]
, 1984 This thesis considers the archaeological evidence for early settlement in Upper Teesdale from its beginnings in the early mesolithic up to the Norman conquest.
Coggins, Denis
core
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Tobacco Regulation through Litigation: The Master Settlement Agreement [PDF]
The 1998 Master Settlement Agreement resolved the unprecedented litigation in which the states sought to recoup the cigarette-related Medicaid costs. The litigation was settled through a combination of negotiated regulatory requirements and financial ...
W. Kip Viscusi, Joni Hersch
core
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
A Survey of the Literature on the WTO Dispute Settlement System [PDF]
This paper surveys the law and economics literature on WTO dispute settlement. As a background, we first briefly lay out main features of the legal framework, and discuss possible roles of a dispute settlement mechanism.
Mavroidis, Petros C., Horn, Henrik
core
, 2021 The CARE project, ‘Community Archaeology in Rural Environments Meeting Societal Challenges’ (CARE- MSoC), is a four-nation research project carrying out archaeological test pit excavations within currently inhabited rural settlements of known or ...
Marciniak, Arkadiusz +6 more
core
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Exploiting Plaintiffs Through Settlement: Divide and Conquer [PDF]
This paper considers settlement negotiations between a single defendant and $N$ plaintiffs when there are fixed costs of litigation. When making simultaneous take-it-or-leave-it offers to the plaintiffs, the defendant adopts a divide and conquer strategy.
Che, Yeon-Koo, Spier, Kathryn
core
BuildingsWith the rapid expansion of Chinese cities, traditional siheyuan in some old urban areas and historic districts have gradually transformed into overcrowded courtyard tenements inhabited primarily by rural migrants.
Mengying Wang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source