Results 101 to 110 of about 449,899 (310)

Modelling the Impact of Blockchain Technology Barriers on Construction Procurement Systems in Nigeria

Advances in Civil Engineering
Blockchain is a decentralised system based on cryptographic procedures and smart contracts that records every transaction and shares it with all parties involved, thereby handling issues of delays and trust.
David Ojimaojo Ebiloma, Opeoluwa Akinradewo, Clinton Ohis Aigbavboa, Babatunde Fatai Ogunbayo   +3 more
doaj   +1 more source

‘Keep learning, keep trying’: exploring food and cultural experiences and supports of Inuvialuit youth in the Inuvialuit Settlement Region

Global Public Health
Country food (CF) and subsistence harvesting are crucial for Inuvialuit of the Inuvialuit Settlement Region, contributing to food security, wellbeing and cultural continuity. However, youth face barriers to participating in these activities, with a shift
Maria Ramirez Prieto, Sonja Ostertag, Kanelsa Noksana, Shayla Arey, Denise Wolki, Susie Memogana, Celina Wolki, Aimee Yurris, Kelly Skinner   +8 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Simulating interbank payment and securities settlement mechanisms with the BoF-PSS2 simulator [PDF]

The simulation technique provides a new means for analysing complex interdependencies in payment and securities settlement processing. The Bank of Finland has developed a payment and settlement system simulator (BoF-PSS2) that can be used for ...
Leinonen, Harry, Soramäki, Kimmo
core  

The behaviour of modern flexible framed structures undergoing differential settlement

, 2010
Modern office buildings are often open plan buildings with a frame consisting of flat RC slabs, RC columns and non-load bearing internal and external partitions and facades.
Smit, Gerrit
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Spatiotemporal Climate–Vegetation Dynamics and the Vegetation Ecological Quality-Based Zoning Under Climate Change: Evidence from the Qinling Mountains

Land
This study analyzed the spatiotemporal dynamics of the vegetation ecological quality under climate change. Focusing on the vegetation conditions, a vegetation ecological quality index was constructed, expressing as the product of vegetation fraction ...
Yishan Xu, Zilin Chen, Lina Jin, Jiangfeng Cao, Zimo Huang, Yanshuo Dong, Binqing Zhai, Xin Wang   +7 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

WTO Dispute Settlement: General Appreciation and the Role of India [PDF]

On 1 January 1995, the Understanding on Rules and Procedures Governing the Settlement of Disputes (DSU) entered into force. Until August 2006, the DSU has since been applied to 348 complaints – more cases than dispute settlement under the GATT 1947 had ...
Zimmermann, Thomas A.
core