Results 81 to 90 of about 1,332,882 (309)

Assessing urban fire risk in the central business district of Dar es Salaam, Tanzania

open access: yesJàmbá, 2010
Buildings as infrastructure along with people’s lives need protection against fire outbreaks. Knowledge on the use of installed facilities is essential in tackling There emergencies, otherwise their installation becomes meaningless.
Yohannes Kachenje   +2 more
doaj   +1 more source

The Burden and Order of Proof in WTO Claims: Evolving Issues [PDF]

open access: yes, 2017
The World Trade Organization (WTO) is one of the best dispute settlement mechanisms in the world. Under WTO rules, aggrieved parties must establish a “prima facie” case before the panel can call on the offending party to respond to the claims.
Ahmad, Zeina, Malkawi, Bashar H.
core   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Agro-ecological monitoring of the territory of the Chelyabinsk agriculture research institute [PDF]

open access: yesBIO Web of Conferences
Agroecological monitoring of lands is an important tool in regulating the development of unfavorable processes of lands suitable for agricultural use. It is a component of land use forecasting. The article is devoted to the organization of agroecological
Ottinger D.M.   +4 more
doaj   +1 more source

An analysis of systemic risk in alternative securities settlement architectures [PDF]

open access: yes
This paper compares securities settlement gross and netting architectures. It studies settlement risk arising from exogenous operational delays and compares settlement failures between the two architectures as functions of the length of the settlement ...
Iori, Giulia
core  

The Grand Compromise: The ANCSA Section 7(i) Settlement Agreement [PDF]

open access: yes, 2017
In 1982, Alaska’s twelve regional Native corporations finalized and executed a settlement agreement ending a decade of litigation involving Section 7(i) of the Alaska Native Claims Settlement Act. The 121-page Settlement Agreement is complex and covers a
Schutt, Aaron M., Schutt, Ethan G.
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Developing a Holistic Approach for Constructing Rural Living Circles in the Loess Plateau—Taking Yongning Village as an Example

open access: yesBuildings
Insufficient public service facilities in rural areas, which leads to failures in meeting the needs of villagers, has become a significant barrier to the high-quality development of rural regions.
Mengying Wang   +6 more
doaj   +1 more source

Guess what: It's the Settlements! [PDF]

open access: yes
Exchanges and other trading platforms are often vertically integrated to carry out trading and settlement as one operation. We show that these vertical silos can prevent the full realization of efficincy gains from horizontal consolidation of trading and
Cyril Monnet, Thorsten Koeppl
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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