Results 21 to 30 of about 466,311 (312)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Frontiers in PsychologyBased on the landscape perception theory and human factors methods, this study adopted eye-tracking and multimodal physiological monitoring to explore the effects of age-friendly rehabilitative landscapes on stress recovery in older adults. A total of 44
Jinghua Dai +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Mechanical Properties of Adjacent Pile Bases in Collapsible Loess under Metro Depot
Applied SciencesMetro transit construction has begun to develop rapidly in northwest China because of the acceleration of urbanization. Accordingly, metro depots are also regarded as an essential auxiliary facility for stopping, operation, and maintenance of trains ...
Xiaohua Liu +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Genetic control of traits determining phosphorus uptake by rice varieties (Oryza sativa L.)
Вавиловский журнал генетики и селекции, 2015 The objectives of this research are: (1) to find genetic material associated with high growth rate and maximum size of root system, (2) to study polymorphism of rice varieties for markers connected with genes defining effective utilization of phosphorus,
J. K. Goncharova, E. M. Kharitonov
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Research on the Vibration Fatigue Characteristics of Ancient Building Wood Materials
BuildingsIn this study, we selected ancient building timber as the research object. A series of static load tests were conducted to analyze the different performances of timber under tensile and compressive loads.
Chunyu Qian +4 more
doaj +1 more source