Results 41 to 50 of about 449,899 (310)

The association between COVID-19 related stressors and mental health in refugees living in Australia

European Journal of Psychotraumatology, 2021
Background: Refugees may be particularly vulnerable to the adverse effects of the COVID-19 pandemic on mental health due to their traumatic pasts and the challenges of the postmigration environment.
Belinda J. Liddell, Meaghan O’Donnell, Richard A. Bryant, Stephanie Murphy, Yulisha Byrow, Vicki Mau, Tadgh McMahon, Greg Benson, Angela Nickerson   +8 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Research on the Vibration Fatigue Characteristics of Ancient Building Wood Materials

Buildings
In this study, we selected ancient building timber as the research object. A series of static load tests were conducted to analyze the different performances of timber under tensile and compressive loads.
Chunyu Qian, Mingze Li, Hongjian Liao, Chenhe Zhang, Hangzhou Li   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

South African Construction Craftsmen’s Perceptions of Effective Personnel Management Practices [PDF]

MATEC Web of Conferences, 2019
The recent skill shortage within South Africa has raised the need for proper management of the available craftsmen in the construction industry, as a large portion of work executed within the industry is done by this set of workers.
Aghimien Douglas, Aigbavboa Clinton, Oke Ayodeji, Makhwathana Mbavhalelo   +3 more
doaj   +1 more source

A dynamic model of settlement [PDF]

Journal of Economic Theory, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Thorsten Koeppl, Cyril Monnet, Ted Temzelides   +2 more
openaire   +5 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Satisfaction of female-headed households on state-led resettlement housing in Kigali: A gender intersectionality lens

Cogent Social Sciences
Female-headed households (FHHs) constitute a heterogeneous social group with diverse resettlement housing needs, expectations, and aspirations. This study intends to expand knowledge on resettlement housing schemes using a gender lens.
Tharcille Dukuzemariya, Wilbard J. Kombe, Tatu Mtwangi-Limbumba   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source