Results 31 to 40 of about 466,311 (312)

Assessment of the sedative effect of various anesthetics in Coregonus Peled (Gmelin, 1789) in aquaculture [PDF]

open access: yesBIO Web of Conferences
The sedative effect of four anesthetic agents in whitefish was studied. It is shown that the effect of anesthetics causes a number of consistent behavioral and physiological reactions in fish, reflecting the change in the state of their body.
Tolmacheva Yulia   +6 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Research on the Space Hierarchy Identification and Optimization Strategies of Villages in Loess Gully Region Based on the Geospatial–Social Network Relationship

open access: yesLand
To address the coordination between social and spatial relationships within villages in the loess gully region, this study developed a joint Geospatial–Social Network analytical approach.
Yulin Ren   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Satisfaction of female-headed households on state-led resettlement housing in Kigali: A gender intersectionality lens

open access: yesCogent Social Sciences
Female-headed households (FHHs) constitute a heterogeneous social group with diverse resettlement housing needs, expectations, and aspirations. This study intends to expand knowledge on resettlement housing schemes using a gender lens.
Tharcille Dukuzemariya   +2 more
doaj   +1 more source

The association between COVID-19 related stressors and mental health in refugees living in Australia

open access: yesEuropean Journal of Psychotraumatology, 2021
Background: Refugees may be particularly vulnerable to the adverse effects of the COVID-19 pandemic on mental health due to their traumatic pasts and the challenges of the postmigration environment.
Belinda J. Liddell   +8 more
doaj   +1 more source

A dynamic model of settlement [PDF]

open access: yesJournal of Economic Theory, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Thorsten Koeppl   +2 more
openaire   +5 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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