Results 31 to 40 of about 94,352 (268)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Study on the Perception of Local Characteristics in Cultural Street Vending Spaces, Taking Xi’an Baxian Temple as an Example

Buildings
The mode of urban renewal in China has changed from incremental expansion to a value-added stage, and the development of cities has increasingly focused on the human experience and quality improvement.
Yingtao Qi, Liping Yue, Tie Guo, Dian Zhou, Yulin Ren, Mengying Wang, Yujia Liu, Yujun Yang   +7 more
doaj   +1 more source

Does proximity to tourist site affect the rental value of residential properties? Empirical evidence from Nigeria [PDF]

MATEC Web of Conferences, 2020
The property market plays a vital role in the economy of any nation. The industry provides jobs, investment opportunities and constructed space for productive activities, among others. Several authors have developed predictive models for the rental value
Oshodi Olalekan, Oyedeji Oyewale, Aigbovboa Clinton   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Mechanical Properties of Adjacent Pile Bases in Collapsible Loess under Metro Depot

Applied Sciences
Metro transit construction has begun to develop rapidly in northwest China because of the acceleration of urbanization. Accordingly, metro depots are also regarded as an essential auxiliary facility for stopping, operation, and maintenance of trains ...
Xiaohua Liu, Mingze Li, Hongjian Liao, Bingyan Huang, Shaohua Liu   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assessment of the sedative effect of various anesthetics in Coregonus Peled (Gmelin, 1789) in aquaculture [PDF]

BIO Web of Conferences
The sedative effect of four anesthetic agents in whitefish was studied. It is shown that the effect of anesthetics causes a number of consistent behavioral and physiological reactions in fish, reflecting the change in the state of their body.
Tolmacheva Yulia, Borisova Elena, Dzyuba Elena, Sukhanova Lyubov, Nebesnykh Ivan, Demyanovich Inna, Demyanovich Konstantin   +6 more
doaj   +1 more source

The association between COVID-19 related stressors and mental health in refugees living in Australia

European Journal of Psychotraumatology, 2021
Background: Refugees may be particularly vulnerable to the adverse effects of the COVID-19 pandemic on mental health due to their traumatic pasts and the challenges of the postmigration environment.
Belinda J. Liddell, Meaghan O’Donnell, Richard A. Bryant, Stephanie Murphy, Yulisha Byrow, Vicki Mau, Tadgh McMahon, Greg Benson, Angela Nickerson   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source