Results 51 to 60 of about 1,332,882 (309)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Parametric Analysis Towards the Design of Micro-Scale Wind Turbines: A Machine Learning Approach

Applied System Innovation
Wind turbine design is an iterative process. Many aspects are considered when designing a wind turbine, including aerodynamic and power performance, structural loads and behavior, and control techniques.
Raneem Mansour, Seifelden Osama, Hazem Ahmed, Mohamed Nasser, Norhan Mahmoud, Amira Elkodama, Amr Ismaiel   +6 more
doaj   +1 more source

"Applications of the Plant Decoration morphology in the ecological paintings production"

Journal of Architecture, Art & Humanistic Science, 2018
The "plant Decoration  morphology " of applied science, which specializes in the study of the shape of the plant and its distinctive exterior to provide designs and products aesthetic and utilitarian.
Noha Afify, Alaa Kamel
doaj   +1 more source

Revisiting Antitrust Limits to Probabilistic Patent Disputes: Strategic Entry and Asymmetric Information [PDF]

, 2010
We consider separately strategic entry and asymmetric information in the design of the settlement policy governing patent disputes, with a focus on Shapiro (2003)’s consumer protection rule.
Chiou, Jing-Yuan, Schmidtke, Richard
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Development of histological detection methods of cottage cheese falsification

BIO Web of Conferences, 2020
Information falsification of fermented milk products is a consumer fraud using inaccurate or distorted product information. The purpose of falsification is to obtain illegal profits by reducing the production cost as a result of the unauthorized ...
Reznichenko Liudmila, Nikolenko Elena, Noskov Sergei, Shcherbinin Roman   +3 more
doaj   +1 more source

Remarks [PDF]

, 2000
The limits of international trade must be understood within the context of the institutional framework of the WTO, in particular, the decision-making and dispute settlement processes.
Jackson, John H.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Psycho-Physiological Effects of Form and Species of Street Vegetation on Human Health

Buildings
Street vegetation is an important component of urban green space which plays a crucial role in promoting human well-being. To examine the impact of different types of street vegetation on individuals’ mental health, we presented two types of four street ...
Xudong Wang, Jingqing Yang, Jiali Mo, Bohan Zhang, Quanquan Zhao, Ge Guo, Lin Cheng   +6 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source