Results 51 to 60 of about 94,352 (268)

Parametric Analysis Towards the Design of Micro-Scale Wind Turbines: A Machine Learning Approach

Applied System Innovation
Wind turbine design is an iterative process. Many aspects are considered when designing a wind turbine, including aerodynamic and power performance, structural loads and behavior, and control techniques.
Raneem Mansour, Seifelden Osama, Hazem Ahmed, Mohamed Nasser, Norhan Mahmoud, Amira Elkodama, Amr Ismaiel   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Yield Stability and Grain Yield Performance of Proso Millet (Panicum miliaceum L.) Genotypes Across Contrasting Years in Northern Kazakhstan

Agriculture
Proso millet (Panicum miliaceum L.) is a drought-tolerant cereal crop with considerable potential for dry-steppe agriculture. This study evaluated grain yield performance and stability of 104 proso millet genotypes originating from 21 countries under ...
Yuri Dolinny, Vladimir Kobernitsky, Timur Savin, Aiman Rysbekova, Vera Volobaeva, Yevgeniya Miller, Tatyana Kobernitskaya, Irina Zhirnova   +7 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development of histological detection methods of cottage cheese falsification

BIO Web of Conferences, 2020
Information falsification of fermented milk products is a consumer fraud using inaccurate or distorted product information. The purpose of falsification is to obtain illegal profits by reducing the production cost as a result of the unauthorized ...
Reznichenko Liudmila, Nikolenko Elena, Noskov Sergei, Shcherbinin Roman   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Psycho-Physiological Effects of Form and Species of Street Vegetation on Human Health

Buildings
Street vegetation is an important component of urban green space which plays a crucial role in promoting human well-being. To examine the impact of different types of street vegetation on individuals’ mental health, we presented two types of four street ...
Xudong Wang, Jingqing Yang, Jiali Mo, Bohan Zhang, Quanquan Zhao, Ge Guo, Lin Cheng   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza

Virology Journal
Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate disease in the event of co-infection.
Ekaterina Stepanova, Irina Isakova-Sivak, Daria Mezhenskaya, Sergei Niskanen, Victoria Matyushenko, Ekaterina Bazhenova, Alexandra Rak, Pei Fong Wong, Polina Prokopenko, Tatiana Kotomina, Elena Krutikova, Sergei Legotskiy, Bogdan Neterebskii, Tatiana Ostroukhova, Konstantin Sivak, Yana Orshanskaya, Kirill Yakovlev, Larisa Rudenko   +17 more
doaj   +1 more source

Clothes as a source of creativity in interior design

Journal of Architecture, Art & Humanistic Science, 2019
The imagination of the artist “designer” plays an important role in the aesthetic creativity of all applied arts; regardless of their types and methods. Without this creativity, the designer can’t express their ideas by using plastic raw material/s which
Nihal Afify, Wael Kamel El Sayed
doaj   +1 more source