Results 31 to 40 of about 801,999 (333)

Evaluating thermal comfort indices for outdoor spaces on a university campus

Scientific Reports
This study evaluates the applicability of three thermal comfort indices—Physiologically Equivalent Temperature (PET), Standard Effective Temperature (SET), and Universal Thermal Climate Index (UTCI)—in various outdoor environments on the campus of Xi’an ...
Wenqiang Jing, Zeming Qin, Teng Mu, Zhemin Ge, Yuting Dong   +4 more
doaj   +1 more source

Improved governance and sustainable urban development Strategic planning holds the key

European Journal of Spatial Development, 2006
The recent focus on improved governance in cities has raised some concerns about the role of urban planning. Questions have been raised on whether good governance is a substitute for planning, and if it is adequate in itself to achieve sustainable ...
Shipra Narang, Lars Reuterswärd
doaj   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Investigation on Influence of Friction Plate Material Properties on Hysteretic Performance and Stability of Friction Dampers

Buildings
Friction dampers are widely used in building seismic protection due to their excellent shock-absorbing performance and reliable operation. To clarify the influence of friction plate material properties on the hysteretic behavior and stability of friction
Fengzhe Jiang, Guangyu Xu, Jianping Liu, Shaohui Dang, Zahid Irshad, Yanchao Yue, Chen Guo   +6 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Optimization of indoor quality and thermal comfort for university classrooms using data-based machine learning [PDF]

E3S Web of Conferences
Improving indoor environment quality on university classrooms is a hot research topic. The on-site experiment was conducted on indoor environmental quality regarding temperature, humidity, air pollutants, light and acoustics during different seasonal ...
Jiang Qiwen, Liu Jialu, Yang Xian
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Research on Shield Tunneling across a River Using a Scale Model

Buildings, 2023
This paper proposes a scale model test to simulate shield tunnel excavation over long distances. The test simulates the whole process of shield tunneling through the Weihe River on Xi’an Metro Line 1, where the tunneling length and diameter reach 100 m ...
Wenxiao Li, Yilei Zhang, Jianxun Ma, Mohammed El Hoseny   +3 more
doaj   +1 more source