Results 31 to 40 of about 257,863 (298)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Evaluating thermal comfort indices for outdoor spaces on a university campus

open access: yesScientific Reports
This study evaluates the applicability of three thermal comfort indices—Physiologically Equivalent Temperature (PET), Standard Effective Temperature (SET), and Universal Thermal Climate Index (UTCI)—in various outdoor environments on the campus of Xi’an ...
Wenqiang Jing   +4 more
doaj   +1 more source

Environmental Effects from Pocket Park Design According to District Planning Patterns—Cases from Xi’an, China

open access: yesAtmosphere, 2022
Rapid urban expansion leads to the continuous deterioration of the urban thermal environment, which endangers the sustainable development of the city; meanwhile, countries all over the world are becoming increasingly interested in the mitigating effects ...
Jiajie Hou   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Microclimate-driven strategies for thermally comfortable university open spaces in cold regions of China

open access: yesScientific Reports
University open spaces are predominantly utilized by students, with outdoor thermal comfort on campus significantly enhancing their physical and mental well-being. This study investigates the thermal perceptions (sensation, comfort, and acceptability) of
Wenqiang Jing   +6 more
doaj   +1 more source

A study on analysing sociospatial distribution and equity in access to urban parks in Bengaluru, India

open access: yesThe Lancet Planetary Health
Background: Given the effect of urbanisation on land use, allocation, and implementation of urban green spaces, we attempt to analyse the sociospatial distribution and equity in access to urban parks in Bengaluru, India, also known as the garden city of ...
Nilanjan Bhor, MPH   +1 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Optimization of the Seismic Performance of a Steel-Concrete Wind Turbine Tower with the Tuned Mass Damper

open access: yesBuildings, 2022
To optimize the seismic performance of a new type of steel-concrete tower, a 120 m steel-concrete composite tower model with a tuned mass damper (TMD) was constructed in ABAQUS for simulation analysis.
Yanchao Yue   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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