Results 141 to 150 of about 3,514 (173)
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Background. Sevelamer carbonate is an improved, buffered form of sevelamer hydrochloride developed for the treatment of hyperphosphataemia in CKD patients.
Stanley Fan
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Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients
Elevated serum phosphorus and calcium are associated with arterial calcification and mortality in dialysis patients. Unlike calcium-based binders, sevelamer attenuates arterial calcification but it is unknown whether sevelamer affects mortality or ...
B N Ling, Steven K Burke
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Background. Sevelamer is a phosphate-binder used effectively for the treatment of hyperphosphatemia in patients treated with dialysis. Objectives. To describe the safety of sevelamer in children with hyperphosphatemia secondary to tumor lysis syndrome ...
Shaker Abdullah +2 more
exaly +2 more sources
Nephron Clinical Practice, 2004
Hyperphosphataemia in patients with chronic renal failure has traditionally been treated with calcium- and aluminium-containing phosphate binders. This article briefly discusses the rationale and complications of these treatments and reviews sevelamer that is a novel non-calcium-, non-aluminium-containing phosphate binder and the evidence to support ...
Jane, Henderson, Paul, Altmann
openaire +2 more sources
Hyperphosphataemia in patients with chronic renal failure has traditionally been treated with calcium- and aluminium-containing phosphate binders. This article briefly discusses the rationale and complications of these treatments and reviews sevelamer that is a novel non-calcium-, non-aluminium-containing phosphate binder and the evidence to support ...
Jane, Henderson, Paul, Altmann
openaire +2 more sources
Annals of Pharmacotherapy, 2010
OBJECTIVE To review the pharmacology, pharmacokinetics, clinical efficacy, safety data, and place in therapy of sevelamer carbonate for the treatment of hyperphosphatemia in patients with chronic kidney disease (CKD).
Mary M, Barna +2 more
openaire +2 more sources
OBJECTIVE To review the pharmacology, pharmacokinetics, clinical efficacy, safety data, and place in therapy of sevelamer carbonate for the treatment of hyperphosphatemia in patients with chronic kidney disease (CKD).
Mary M, Barna +2 more
openaire +2 more sources
Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats.BackgroundHyperphosphatemia is associated with severe complications, including ectopic calcification of soft tissues, secondary ...
Nobuo Nagano +2 more
exaly +2 more sources

