Results 21 to 30 of about 3,861 (173)

Protein-Bound Uremic Toxins Lowering Effect of Sevelamer in Pre-Dialysis Chronic Kidney Disease Patients with Hyperphosphatemia: A Randomized Controlled Trial

Toxins, 2021
P-cresyl sulfate and indoxyl sulfate are strongly associated with cardiovascular events and all-cause mortality in chronic kidney disease (CKD). This randomized controlled trial was conducted to compare the effects between sevelamer and calcium carbonate
Kullaya Takkavatakarn, Pongpratch Puapatanakul, Jeerath Phannajit, Warumphon Sukkumme, Pajaree Chariyavilaskul, Patita Sitticharoenchai, Asada Leelahavanichkul, Pisut Katavetin, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Paweena Susantitaphong   +10 more
doaj   +1 more source

The Therapeutic Effects of Sevelamer on Blood Sugar, HbA1c, Lipid Profile, and hs-CRP in Patients with Diabetic Nephropathy [PDF]

Journal of Nephropathology, 2018
Background: Diabetic nephropathy (DN) is one of the major complications of diabetes. Hyperglycemia, inflammation and oxidative stress as well as advanced glycation end products (AGEs) are reported as the risk factors for DN. Sevelamer has shown promising
Sosan Mohammadi Kebar, Afshan Shargi, Bahman Bashardoust, Manouchehr Iranparvar, Hossein Fekri, Afshin Habibzadeh   +5 more
doaj   +1 more source

Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization

Drug Delivery, 2022
Arsenic trioxide (As2O3, ATO) has limited therapeutic benefit to treat solid tumors, whether used alone or in combination. Nanoscale drug delivery vehicles have great potential to overcome the limitation of the utility of ATO by rapid renal clearance and
Qiu-Chen Bi, Jian-Jun Tang, Jun Zhao, Yang-Feng Lv, Zhi-Qiang Deng, Hong Chen, Yu-Hua Xu, Chuan-Sheng Xie, Qing-Rong Liang, Rong-Guang Luo, Qun Tang   +10 more
doaj   +1 more source

Colonic Mass Secondary to Sevelamer-associated Rectal Ulcer

The Korean Journal of Gastroenterology, 2021
The phosphorous balance is clinically important in increasing the long-term outcomes and preventing complications of end-stage renal disease. Sevelamer is a phosphate binder used widely to regulate hyperphosphatemia.
Jin Hee Lee, Sang Hyoung Park, Jin Ho Shin, Seung-Mo Hong, Jin Hwa Park, Sung Wook Hwang, Dong-Hoon Yang, Jeong-Sik Byeon, Seung-Jae Myung, Byong Duk Ye, Suk-Kyun Yang   +10 more
doaj   +1 more source

Effect of Sevelamer on Calciprotein Particles in Hemodialysis Patients: The Sevelamer Versus Calcium to Reduce Fetuin-A-Containing Calciprotein Particles in Dialysis (SCaRF) Randomized Controlled Trial

Kidney International Reports, 2020
Introduction: Calciprotein particles (CPPs) are potentially modifiable mediators of phosphate toxicity in patients with kidney disease. We compared the effects of calcium carbonate (CC) and the non–calcium-based phosphate binder sevelamer on CPP levels ...
Edward R. Smith, Fei Fei M. Pan, Tim D. Hewitson, Nigel D. Toussaint, Stephen G. Holt   +4 more
doaj   +1 more source

The Influence of Sevelamer Hydrochloride and Calcium Carbonate on Markers of Inflammation and Oxidative Stress in Hemodialysis at Six Months of Follow-Up

Frontiers in Medicine, 2021
Patients with end-stage renal disease (ESRD) present alterations in mineral and bone metabolism. Hyperphosphatemia in ESRD is considered an independent risk factor for cardiovascular disease (CVD), increasing morbidity, and mortality.
Elodia Nataly Díaz-De la Cruz, José Ignacio Cerrillos-Gutiérrez, Andrés García-Sánchez, Carlos Gerardo Prado-Nevárez, Jorge Andrade-Sierra, Basilio Jalomo-Martínez, Adriana Banda-López, Enrique Rojas-Campos, Alejandra Guillermina Miranda-Díaz   +8 more
doaj   +1 more source

Sevelamer-induced Gastrointestinal Mucosal Injury: A Critical Review for Clinicians. [PDF]

J Community Hosp Intern Med Perspect
Sevelamer is a non-absorbable polymer used to treat hyperphosphatemia in individuals with end-stage renal disease (ESRD) undergoing hemodialysis. The deposition of sevelamer crystals in the gastrointestinal (GI) tract, especially in the colon, can cause ...
Bathobakae L, Phuu P, Yasin S, Bashir R, Escobar J, Yuridullah R, Melki G, Elagami M, Amer K, Cavanagh Y, Baddoura W.   +10 more
europepmc   +2 more sources

An unusual combination of neurological manifestations and sudden vision loss in a child with familial hyperphosphatemic tumoral calcinosis

Annals of Indian Academy of Neurology, 2019
Hyperphosphatemia in the absence of renal failure is an unusual occurrence, particularly in children, but is a common primary feature of familial hyperphosphatemic tumor calcinosis.
Lokesh Lingappa, Shoji Ichikawa, Amie K Gray, Dena Acton, Michael J Evans, Rajsekara Chakravarthi Madarasu, Ramesh Kekunnaya, Sirisharani Siddaiahagari   +7 more
doaj   +1 more source

Effect of sevelamer on serum phosphorus levels in chronic kidney disease and hemodialysis patients; a systematic review and meta-analysis [PDF]

Journal of Nephropathology
Introduction: Hyperphosphatemia is an independent risk factor for mortality in chronic kidney disease (CKD) patients. Objectives: This systematic review and meta-analysis aimed to investigate the effect of Sevelamer on serum phosphorus levels in CKD and ...
Farshad Gharebakhshi, Mohammad Hossein Taklif, Arash Izadpanah Ghahremani, Mohamad Khaledi, Sara Abbasian, Seyedeh Mahsa Shariati Sough, Fatemeh Vashahi Torfi, Hamidreza Khodabandeh, Elnaz Hajian   +8 more
doaj   +1 more source

Evaluation of the safety and efficacy of transarterial sevelamer embolization in a rabbit liver cancer model: A challenge on the size rule for vascular occlusion

Frontiers in Bioengineering and Biotechnology, 2022
As the most efficient method to treat hepatocellular carcinoma in the immediate or advanced stage, transarterial chemoembolization (TACE) is coming into the era of microsphere (MP).
Hong Chen, Chuan-Sheng Xie, Yan-Shu Li, Zhi-Qiang Deng, Yang-Feng Lv, Yang-Feng Lv, Qiu-Chen Bi, Qiu-Chen Bi, Jian-Jun Tang, Rong-Guang Luo, Qun Tang, Qun Tang   +11 more
doaj   +1 more source