Results 21 to 30 of about 5,511 (190)

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ, Dandekar, S, Gaulke, CA, Glavan, TW, Goulart, LR, Hirao, LA, Jiang, G, Raffatellu, M, Sankaran-Walters, S, Santos Rocha, C   +9 more
core   +2 more sources

Sevelamer-associated ischemic colitis with perforation

Gastroenterology Insights, 2015
We present a case of an 83-year-old woman with end-stage renal disease and hyperphosphatemia treated with sevelamer carbonate, who underwent subtotal colectomy for diffuse bowel necrosis and two perforations in the transverse colon.
Rachel Hudacko, Peter Kaye
doaj   +1 more source

Response of different PTH assays to therapy with sevelamer or CaCO and active vitamin D sterols [PDF]

, 2009
Amino-terminally truncated parathyroid hormone (PTH) fragments are detected to differing degrees by first- and second-generation immunometric PTH assays (PTH-IMAs), and acute changes in serum calcium affect the proportion of these fragments in ...
Katherine Wesseling-Perry, G. Chris Harkins, He-Jing Wang, Shobha Sahney, Barbara Gales, Robert M. Elashoff, Harald Jüppner, Isidro B. Salusky, LD Quarles, H Jüppner, JH Brossard, R Lepage, P Boudou, A Fujimori, E Slatopolsky, L Nguyen-Yamamoto, P D’Amour, MR John, MC Monier-Faugere, IB Salusky, SC Waller, G Coen, KJ Martin, MC Monier-Faugere, IB Salusky, IB Salusky, AM Parfitt, RA Upton, GM Chertow, GA Block, GA Block, GA Block, DS Milliner, BY Liu, P D’Amour   +34 more
core   +1 more source

Emerging Effects of Sevelamer in Chronic Kidney Disease

Kidney & Blood Pressure Research, 2013
Sevelamer, a non-absorbable anion exchange resin, is used to control hyperphosphatemia in chronic kidney disease (CKD) by binding to dietary phosphate in the gastrointestinal tract.
Ryota Ikee, Masataka Tsunoda, Naomi Sasaki, Naritsugu Sato, Nobuo Hashimoto   +4 more
doaj   +1 more source

Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization

Drug Delivery, 2022
Arsenic trioxide (As2O3, ATO) has limited therapeutic benefit to treat solid tumors, whether used alone or in combination. Nanoscale drug delivery vehicles have great potential to overcome the limitation of the utility of ATO by rapid renal clearance and
Qiu-Chen Bi, Jian-Jun Tang, Jun Zhao, Yang-Feng Lv, Zhi-Qiang Deng, Hong Chen, Yu-Hua Xu, Chuan-Sheng Xie, Qing-Rong Liang, Rong-Guang Luo, Qun Tang   +10 more
doaj   +1 more source

Genetic Determinants of Phosphate Response in Drosophila [PDF]

, 2012
Phosphate is required for many important cellular processes and having too little phosphate or too much can cause disease and reduce life span in humans.
A Bevington, A Friedman, A Kaffman, A Martin, Adam Friedman, Arunachalam Vinayagam, Bonnie Berger, C Bergwitz, C Bergwitz, C Bergwitz, Charles DeRobertis, Clemens Bergwitz, D Baldridge, D Nair, DA Mason, E Hesse, E Ito, E Laplantine, E Moallem, E Sprecher, F Rossi, Fanis Missirlis, G Huang, GM Chertow, GR Beck Jr, H Steller, HS Tenenhouse, HT Gazda, HW Zhao, IC Lopez-Mejia, IT Flockhart, J Tower, JA Dow, JJ Tong, Joanne Huang, Jonathan Cohen, JR Stubbs, JT Eppig, K Engel, K Mansfield, K Morishita, LA Perkins, Lawrence B. Mensah, Lizabeth A. Perkins, M Dinur, M Julien, M Mizobuchi, M Nechama, M Nechama, M Ohnishi, M Ohnishi, M Yamazaki, Mark J. Wee, MB Eisen, ME Kraus, ME Lenburg, Meghana Kulkarni, Michael Schnall-Levin, MS Razzaque, MY Zhang, Norbert Perrimon, OJ Dunn, OM Gutierrez, P Ferrigno, PR Gardner, R Kilav, R Lyne, RD Page, RK Smith, RS Edgecomb, S Jan De Beur, S Khoshniat, S Yanagawa, SC Hou, SE McGuire, SH Chang, Stephanie E. Mohr, Sumi Sinha, TM Schroeder, VI Perez, VI Perez, VR Chintapalli, W Huang da, Y Hu, Y Oshima, Y Yoshiko, Yanhui Hu   +86 more
core   +4 more sources

Effect of sevelamer on serum phosphorus levels in chronic kidney disease and hemodialysis patients; a systematic review and meta-analysis [PDF]

Journal of Nephropathology
Introduction: Hyperphosphatemia is an independent risk factor for mortality in chronic kidney disease (CKD) patients. Objectives: This systematic review and meta-analysis aimed to investigate the effect of Sevelamer on serum phosphorus levels in CKD and ...
Farshad Gharebakhshi, Mohammad Hossein Taklif, Arash Izadpanah Ghahremani, Mohamad Khaledi, Sara Abbasian, Seyedeh Mahsa Shariati Sough, Fatemeh Vashahi Torfi, Hamidreza Khodabandeh, Elnaz Hajian   +8 more
doaj   +1 more source

Effect of Sevelamer on Calciprotein Particles in Hemodialysis Patients: The Sevelamer Versus Calcium to Reduce Fetuin-A-Containing Calciprotein Particles in Dialysis (SCaRF) Randomized Controlled Trial

Kidney International Reports, 2020
Introduction: Calciprotein particles (CPPs) are potentially modifiable mediators of phosphate toxicity in patients with kidney disease. We compared the effects of calcium carbonate (CC) and the non–calcium-based phosphate binder sevelamer on CPP levels ...
Edward R. Smith, Fei Fei M. Pan, Tim D. Hewitson, Nigel D. Toussaint, Stephen G. Holt   +4 more
doaj   +1 more source

Colonic Mass Secondary to Sevelamer-associated Rectal Ulcer

The Korean Journal of Gastroenterology, 2021
The phosphorous balance is clinically important in increasing the long-term outcomes and preventing complications of end-stage renal disease. Sevelamer is a phosphate binder used widely to regulate hyperphosphatemia.
Jin Hee Lee, Sang Hyoung Park, Jin Ho Shin, Seung-Mo Hong, Jin Hwa Park, Sung Wook Hwang, Dong-Hoon Yang, Jeong-Sik Byeon, Seung-Jae Myung, Byong Duk Ye, Suk-Kyun Yang   +10 more
doaj   +1 more source

The intestine and the kidneys : a bad marriage can be hazardous [PDF]

, 2015
The concept that the intestine and chronic kidney disease influence each other, emerged only recently. The problem is multifaceted and bidirectional. On one hand, the composition of the intestinal microbiota impacts uraemic retention solute production ...
Glorieux, Griet, Vanholder, Raymond
core   +1 more source