Results 41 to 50 of about 5,511 (190)
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Microbiota signatures in type-2 diabetic patients with chronic kidney disease - A Pilot Study [PDF]
The human microbiota is paramount for normal host physiology. Altered host-microbiome interactions are part of the pathogenesis of numerous common ailments.
Chifiriuc, Mariana Carmen +9 more
core +1 more source
Association of serum fetuin-A and biochemical parameters in hemodialysis patients. [PDF]
Fetuin-A, a hepatic glycoprotein present in the circulation, is a potential inhibitor for systemic calcification. The main aim of this study was to evaluate the association between fetuin-A and other biochemical parameters as facilitator factors for ...
Besharat, S. +5 more
core +2 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Introduction: Lanthanum carbonate (LC) and sevelamer hydrochloride (SH) are non-calcium-based phosphate binders (NCPB), used to manage hyperphosphatemia in patients with chronic kidney disease.
Asrar Khan +6 more
doaj +1 more source
Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]
Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi +2 more
core
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Hyperphosphatemia is a significant risk factor for the development of ectopic calcification and coronary artery diseases in patients on hemodialysis (HD), and must be controlled with the use of phosphate binders.
Farrokhlagha Ahmadi +3 more
doaj +1 more source
A Perfect Storm in Mineral Handling
Introduction One of the commonest complications of end‐stage renal disease (ESRD) is the disruption of normal mineral trafficking, with a major perturbation in the handling of calcium and phosphate. Background Here, we report a patient who presented some time ago along with his imaging, with some of the worst sequelae of these issues.
Wael L. Jebur +2 more
wiley +1 more source
High serum levels of gut-derived uremic toxins, especially p-cresyl sulfate (pCS), indoxyl sulfate (IS) and indole acetic acid (IAA), have been linked to adverse outcomes in patients with chronic kidney disease (CKD).
Youssef Bennis +10 more
doaj +1 more source

