Results 61 to 70 of about 3,514 (173)
Cardiovascular Effects of Sevelamer in Stage 3 CKD
, 2013 Serum phosphate independently predicts cardiovascular mortality in the general population and CKD, even when levels are in the normal range. Associations between serum phosphate, arterial stiffness, and left ventricular (LV) mass suggest a possible ...
Townend, Jonathan N +8 more
core +1 more source
International Journal of Nephrology, 2018 Background. Hyperphosphatemia in chronic kidney disease (CKD) patients is often treated with calcium carbonate (CaCO3) despite the fact that CaCO3 is associated with increased calcium load and potentially increased cardiovascular risk.
B. L. Goh, A. Soraya, A. Goh, K. L. Ang
doaj +1 more source
Sevelamer-Induced Gastrointestinal Injury Presenting as Gastroenteritis [PDF]
, 2018 End-stage renal disease (ESRD) is a common disease encountered in clinical practice and is associated with increasing metabolic derangements through disease progression.
Matthew Robles +2 more
core +2 more sources
Chronic kidney disease and valvular heart disease: State of the art
Physiological Reports, Volume 13, Issue 18, September 2025.Abstract Chronic kidney disease (CKD) and valvular heart disease (VHD) frequently coexist and are associated with a significant increase in morbidity and mortality. Their interplay is complex and multifactorial, involving shared pathophysiological mechanisms such as chronic inflammation, mineral and bone disorder, vascular and valvular calcification ...
S. Saltarocchi +6 more
wiley +1 more source
, 2003 OBJECTIVE: To evaluate in patients with chronic renal failure (CRF) the effectiveness and the costs of sevelamer, a cationic polymer calcium- and aluminum-free, that is a new gastrointestinal phosphate binder.
Ferraz, Marcos B. +3 more
core +1 more source
Effect of Sevelamer on Mineral and Lipid Abnormalities in Hemodialysis Patients
Saudi Journal of Kidney Diseases and Transplantation, 2008 We conducted a prospective study in hemodialysis patients to assess the safety and efficacy of sevelamer, a non-absorbable phosphate binding polymer free of calcium and aluminum, in lowering serum phosphorus, serum intact parathyroid hormone, and serum ...
Hamida Fethi +8 more
doaj
Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded
MedComm, Volume 6, Issue 7, July 2025.Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin +8 more
wiley +1 more source
Nonphosphate-binding effects of sevelamer--are they of clinical relevance?
, 2008 Sevelamer is an ion-exchanging resin that binds phosphate in the gut. Because it does so without increasing the calcium load, treatment with sevelamer may lead to less vascular calcification and better survival in chronic kidney disease patients. However,
Lindholm, Bengt +5 more
core +1 more source
Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution
Small, Volume 21, Issue 21, May 26, 2025.This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani +8 more
wiley +1 more source
, 2003 Treatment of hyperphosphatemia with sevelamer hydrochloride in hemodialysis patients: A comparison with calcium acetate.BackgroundSevelamer hydrochloride is a recently approved calcium- and aluminium-free phosphate binder.
Cerezo, Sebastián +2 more
core +1 more source