Results 71 to 80 of about 3,861 (173)

Sevelamer hydrochloride and coronary artery calcification in chronic hemodialysis patients: a new mechanism of action

The Egyptian Journal of Internal Medicine, 2015
Background The non-calcium-based phosphate binder sevelamer hydrochloride was developed to provide chronic kidney disease patients with a polymer capable of managing hyperphosphatemia without an increase in the calcium load.
Bahaa Eldin Zayed, Hussein El-Fishawy, Amal R Al-Shihaby, Mohamed A Salem, Usama A.A. Sharaf El Din, Mona Mansour   +5 more
doaj   +1 more source

Sevelamer-Induced Gastrointestinal Injury Presenting as Gastroenteritis [PDF]

, 2018
End-stage renal disease (ESRD) is a common disease encountered in clinical practice and is associated with increasing metabolic derangements through disease progression.
Matthew Robles, Jared Magee, Peter Dunaway   +2 more
core   +2 more sources

Use of phosphate binders in end-stage renal disease: An experience from a secondary care hospital in United Arab Emirates

Journal of Pharmacy and Bioallied Sciences, 2019
Objective: Hyperphosphatemia in end-stage renal disease (ESRD) is associated with many serious patient-level consequences including cardiovascular events and mortality.
Syed Arman Rabbani, Sathvik B Sridhar, Padma G M Rao, Martin T Kurian, Basset E Essawy   +4 more
doaj   +1 more source

Sevelamer worsen metabolic acidosis in hemodialysis patients

, 2006
Background: Sevelamer hydrochloride, a major phosphate binder for patients on maintenance hemodialysis (MHD) is associated with reduced serum bicarbonate concentration due to hydrochloric acid release in the gut and to the binding of short chain fatty ...
Cirillo M., Di Stazio E., Santoro D., Correale G., Ciacci C., De Santo N. G., Perna A., Iacono G., Frangiosa A., Di Meglio E., Savica V., Marino A., Stellato D., Anastasio P.   +13 more
core  

Sevelamer worsens metabolic acidosis in hemodialysis patients.

, 2006
Background: Sevelamer hydrochloride, a major phosphate binder for patients on maintenance hemodialysis (MHD) is associated with reduced serum bicarbonate concentration due to hydrochloric acid release in the gut and to the binding of short chain fatty ...
CIACCI C, ANASTASIO P, DI MEGLIO E, CORREALE G, STELLATO D, CIRILLO M., PERNA A, MARINO A, SANTORO, Domenico, DI STAZIO E, DE SANTO NG, IACONO G, FRANGIOSA A, SAVICA, Vincenzo   +13 more
core  

Cost-Effectiveness Analysis for the Treatment of Hyperphosphatemia in Predialysis Patients: Calcium-Based versus Noncalcium-Based Phosphate Binders

International Journal of Nephrology, 2018
Background. Hyperphosphatemia in chronic kidney disease (CKD) patients is often treated with calcium carbonate (CaCO3) despite the fact that CaCO3 is associated with increased calcium load and potentially increased cardiovascular risk.
B. L. Goh, A. Soraya, A. Goh, K. L. Ang
doaj   +1 more source

Fibroblast growth factor 23 and parathyroid hormone after treatment with active vitamin D and sevelamer carbonate in patients with chronic kidney disease stage 3b, a randomized crossover trial

BMC Nephrology, 2012
Background Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that is secreted from bone and serum level increases as renal function declines.
Bleskestad Inger H, Bergrem Harald, Hartmann Anders, Godang Kristin, Gøransson Lasse G   +4 more
doaj   +1 more source

Forest plot of sevelamer vs. calcium phosphate binders on ACS change.

, 2015
Forest plot of sevelamer vs. calcium phosphate binders on ACS change.
Yongming Zhou (429711), Xun Liu (285130), Yanbing Chen (778063), Yanni Wang (482708), Tanqi Lou (285134), Caixia Wang (394572), Shaomin Li (778062)   +6 more
core   +1 more source

Gastric pH, sevelamer hydrochloride and omeprazole

, 2005
Aims: Sevelamer hydrochloride is a polymer containing multiple amines (40% amine hydrochloride) separated by one carbon from the polymer backbone, and it is not absorbed by the intestine.
C. Del Corso, A. Rossi, A. Capitanini, M. Gallieni, F. Osteri, A. Lupi, I. Petrone, M. Straniti   +7 more
core   +1 more source

Sevelamer reduces calcium load and maintains a low calcium-phosphorus ion product in dialysis patients

, 2001
Sevelamer HCl, a non-aluminum, non-calcium containing hydrogel, has proved an effective phosphate binder in North American hemodialysis patients. This single-center, open-label, dose titration study assessed the efficacy of sevelamer in a cohort of ...
ZONI, ULISSE GIUSEPPE, M. Cozzolino, M. Gallieni, P. Carpani, D. Brancaccio   +4 more
core   +1 more source