Results 91 to 100 of about 3,514 (173)

Biomechanical properties of bones from rats treated with sevelamer [Biomehanička svojstva kostiju štakora tretiranih sevelamerom]

, 2011
Sevelamer hydrochloride is used for ten years in patients on dialysis as a phosphate binder. We have previously shown that oral application of sevelamer prevents the bone loss and increases the bone volume in ovariectomized rats. In this study we further
Tikvica, Ana, Brnčić, Mladen, Vukičević, Slobodan, Drača, Nataša, Eljuga, Domagoj, Semenski, Damir   +5 more
core  

Analisi costo/efficacia di sevelamer nel trattamento dell’iperfosforemia del paziente in dialisi

, 2004
Dialysis-associated hyperphosphatemia has been treated with chelating calcium salts, in particular with calcium carbonate. A new option for the management of this problem is represented by sevelamer, a chelating agent which contains no calcium and no ...
Barbone, Gaia Santagostino, Giotta, Nicola, Eandi, Mario   +2 more
core   +1 more source

Sevelamer in a diabetologist's perspective:A phosphate-binding resin with glucose-lowering potential

, 2015
Sevelamer is a calcium-free and metal-free phosphate-binding oral drug used in the management of hyperphosphataemia in chronic kidney disease. Preclinical and clinical trials have shown glucose and lipid-lowering effects of sevelamer, thereby giving rise
Hansen, M., Sonne, D. P., Rohde, U., Brønden, A., Knop, Filip K., Vilsbøll, T.   +5 more
core   +1 more source

Development and Validation of a Gas Chromatography Method for the Trace Level Determination of Allylamine in Sevelamer Hydrochloride and Sevelamer Carbonate Drug Substances

, 2013
A capillary gas chromatography method using a flame ionization detector has been developed for the trace analysis of allylamine (AA) in sevelamer hydrochloride (SVH) and sevelamer carbonate (SVC) drug substances. The method utilized a mega bore capillary
Hemant SHARMA, Himabindu GANDHAM, Annapurna NOWDURI, Raju KADIYALA, Pavan KOTHAPALLI, Madhava PEDDOLLA, Shankar BUDETI, Pradeep RAJPUT   +7 more
core   +1 more source

Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia

, 2003
Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia.BackgroundIn chronic renal failure (CRF), hyperphosphatemia and an elevated calcium-phosphate product are associated with vascular calcification ...
E. Slatopolsky, J. Finch, Staniforth, Mark E., A. S. Dusso, S. K. Burke, M. E. Staniforth, H. Liapis, Burke, Steven K., Dusso, Adriana S., M. Cozzolino, Finch, Jane, Liapis, Helen, Cozzolino, Mario, Slatopolsky, Eduardo   +13 more
core   +1 more source

Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

, 2018
Aims: Sevelamer, a non-absorbable amine-based resin used for treatment of hyperphosphataemia, has been demonstrated to have a marked bile acid-binding potential alongside beneficial effects on lipid and glucose metabolism.
Hansen, Morten, Valentina Tremaroli, Hansen, M., Gabe, M. N., Tremaroli, Valentina, Mikkelsen, K., Sonne, D. P., Jens J. Holst, Mikkelsen, Kristian, Brønden, Andreas, Hao Wu, Bäckhed, Fredrik, Wu, Hao,, Holst, J. J., Rosenkilde, Mette, Holst, Jens J., Jens F. Rehfeld, Tremaroli, Valentina,, Rosenkilde, M., Christoffer Våben, Mette Rosenkilde, Vilsbøll, Tina, Våben, Christoffer, Bronden, A., Gabe, Maria N., Andreas Brønden, Wu, Hao, Rehfeld, Jens F., Morten Hansen, Kristian Mikkelsen, Fredrik Bäckhed, David P. Sonne, Bäckhed, Fredrik,, Filip K. Knop, Tina Vilsbøll, Rehfeld, J. F., Vaben, C., Sonne, David P., Vilsboll, T., Knop, F. K., Knop, Filip K., Maria N. Gabe   +41 more
core   +1 more source

Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

AIM: Bile acid sequestrants are cholesterol-lowering drugs, which also improve glycaemic control in people with type 2 diabetes. The mechanism behind the glucose-lowering effect is unknown but has been proposed to be mediated by increased glucagon-like ...
Hartmann, Bolette, Holst, Jens J., Sonne, David P., Ellegaard, Anne-Marie, Rehfeld, Jens F., Haddouchi, Abdullah E., Vilsbøll, Tina, Knop, Filip K., Nerild, Henriette H., Brønden, Andreas   +9 more
core   +1 more source

Real-World Evidence for Sevelamer vs Calcium-Containing Phosphate Binders in Long-Term Effectiveness and Safety Among Patients with Non-Dialysis CKD: The REVEAL Study. [PDF]

Adv Ther
Li P, Li C, Liang S, Sun X, Guo X, Xu X, Hao L, Chen X, Feng Z, Cai G.   +9 more
europepmc   +1 more source

Comparison of the effects of non-calcium and calcium-based phosphate binders on fibroblast growth factor-23 levels in patients with CKD-mineral and bone disorder: a meta-analysis of randomized controlled trials. [PDF]

BMC Nephrol
Cha S, Baek M, Jung C, Kim H.
europepmc   +1 more source

Assessing the real-world drug safety of sevelamer for hyperphosphatemia: Insights from a comprehensive analysis of the FDA adverse event reporting system (FAERS) database. [PDF]

Medicine (Baltimore)
Shao X, Yang H, Tan C, Liu J, Zhou L.
europepmc   +1 more source