Results 141 to 150 of about 56,993 (185)

Inflammation and Dysregulated Bone Turnover Confound Serum ICAM-1 as a Cardiovascular Marker in Hemodialysis. [PDF]

open access: yesBiomolecules
Divani M   +8 more
europepmc   +1 more source

Acute renal failure after dietary change - a case report. [PDF]

open access: yesBMC Nephrol
Jankowski E   +5 more
europepmc   +1 more source

Gastric pH, sevelamer hydrochloride and omeprazole

open access: yesClinical Nephrology, 2005
Sevelamer hydrochloride is a polymer containing multiple amines (40% amine hydrochloride) separated by one carbon from the polymer backbone, and it is not absorbed by the intestine. These amines are partially protonated and interact with phosphate molecules through ionic and hydrogen bonding, therefore reducing phosphate absorption and lowering serum ...
A. Capitanini   +7 more
core   +5 more sources
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Endotoxin-Binding Affinity of Sevelamer Hydrochloride

American Journal of Nephrology, 2008
<i>Background:</i> Sevelamer hydrochloride has been shown to attenuate circulating biomarkers of inflammation in patients with chronic kidney failure. We hypothesize that sevelamer hydrochloride binds bacterial endotoxin (ET) resulting in a decrease in ET levels and cytokine production.
Bertrand Jaber
exaly   +3 more sources

Comparison of Sevelamer Hydrochloride and Sevelamer Carbonate: Risk of Metabolic Acidosis and Clinical Implications

Pharmacotherapy, 2009
Hyperphosphatemia is highly prevalent in patients with chronic kidney disease (CKD), particularly in those with advanced or end‐stage renal disease. Sevelamer hydrochloride is an ion‐exchange resin that reduces serum phosphorus concentrations. The agent also produces favorable lipid profile effects and does not cause hypercalcemia.
Brian Shepler
exaly   +3 more sources

Effects of Sevelamer Hydrochloride and Calcium Acetate on the Oral Bioavailability of Ciprofloxacin

American Journal of Kidney Diseases, 2003
The oral bioavailability of ciprofloxacin is significantly decreased when administered with calcium carbonate. Sevelamer hydrochloride is a phosphate-binding cationic polymer that is devoid of calcium. The authors conducted a 3-way, randomized, crossover study to determine the effects of sevelamer hydrochloride and calcium acetate on the relative oral ...
Brian R Overholser, Sharon M Moe
exaly   +3 more sources

Buffering Effects of Calcium Carbonate as Clarified by Sevelamer Hydrochloride Monotherapy

Therapeutic Apheresis and Dialysis, 2008
Abstract:  This study was undertaken to examine the necessity of taking into account the acid–base balance to ensure safe switching from calcium carbonate to sevelamer hydrochloride in hemodialysis patients. Forty‐two hemodialysis patients were divided into two groups: the sevelamer hydrochloride therapy group (n = 18; “monotherapy group”) and the ...
Takao Koike
exaly   +3 more sources

Sevelamer Hydrochloride Exacerbates Metabolic Acidosis in Hemodialysis Patients, Depending on the Dosage

Therapeutic Apheresis and Dialysis, 2007
Abstract:  Sevelamer hydrochloride, as a phosphate binder that contains neither aluminum nor calcium, is expected to improve the prognosis of dialysis patients. However, sevelamer hydrochloride has been reported to lower the serum bicarbonate level.
Hiroaki Matsuda   +2 more
exaly   +3 more sources

Increase in Serum Magnesium Level in Haemodialysis Patients Receiving Sevelamer Hydrochloride

International Urology and Nephrology, 2005
Clinical studies have shown that sevelamer hydrochloride improves lipid profiles and attenuates the progression of the cardiovascular calcifications in haemodialysis patients. It is known that both of these properties are associated with increased magnesium levels. The effect of sevelamer on serum magnesium level is not well documented. The aim of this
Efstathios Mitsopoulos, Stavros Zanos
exaly   +3 more sources

Introduction to Sevelamer Hydrochloride and its Clinical Effects

Therapeutic Apheresis and Dialysis, 2005
Abstract:  Sevelamer hydrochloride (SH) is widely used for the treatment of hyperphosphatemia in patients with renal failure who are on maintenance hemodialysis. In this study, we investigated the clinical effects of SH, administered as either monotherapy or combined with a calcium carbonate formulation, on the metabolism of calcium (Ca) and phosphorus
Hideki, Tahara   +5 more
openaire   +2 more sources

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