Results 161 to 170 of about 56,993 (185)
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Impact of sevelamer hydrochloride on serum magnesium concentrations in hemodialysis patients
Magnesium Research, 2016Serum Mg levels are elevated in patients with renal insufficiency: harmful effects of hypomagnesemia have been reported in patients receiving hemodialysis (HD). In this cross-sectional study, which included 86 HD patients (male : female = 56:30, age 68 ± 12 years), we examined the clinical factors associated with serum Mg levels, with a focus on ...
Ryota, Ikee +4 more
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Sevelamer hydrochloride: a calcium- and metal-free phosphate binder
Therapy, 2005Sevelamer hydrochloride is a nonabsorbed, calcium- and metal-free phosphate binder, used to bind phosphate and prevent phosphate accumulation in patients with kidney failure. Sevelamer hydrochloride has been an important alternative to calcium-based phosphate binders, because calcium-based binders result in increased gastrointestinal calcium absorption
Anthony J Bleyer, James M. Balwit
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Homocysteine and folic acid levels in hemodialysis patients treated with sevelamer hydrochloride
Clinical Nephrology, 2010Folic acid deficiency has been reported to elevate plasma homocysteine levels and result in hyperhomocystinemia, which is an independent risk factor for cardiovascular disease. Sevelamer hydrochloride has the potential to bind with folic acid. To determine this effect of sevelamer hydrochloride on plasma homocysteine levels, change in serum folic acid ...
S, Goto, H, Fujii, J-I, Kim, M, Fukagawa
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Long‐term comparison of sevelamer hydrochloride to calcium‐containing phosphate binders
Nephrology, 2006SUMMARYAim: In patients with end‐stage renal disease (ESRD), hyperphosphataemia and an elevated calcium‐phosphorus (Ca‐P) product contribute to morbidity and mortality. Suggested target goals for serum phosphorus concentration and calcium‐phosphorus product have recently been lowered.
Ursula C, Brewster +3 more
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Relative in Vitro Efficacy of the Phosphate Binders Lanthanum Carbonate and Sevelamer Hydrochloride
Journal of Pharmaceutical Sciences, 2007The high tablet burden and poor compliance associated with phosphate-binding drugs has led to a search for more potent agents. In vitro-binding studies were performed on the recently introduced binder, lanthanum carbonate (LC; Fosrenol), to compare its phosphate-binding affinity with sevelamer hydrochloride (SH; Renagel).
Autissier V, Damment SJP, Henderson RA
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[Sevelamer hydrochloride prevents ectopic calcification of blood vessels].
Clinical calcium, 2005Sevelamer hydrochloride is a non-absorbed calcium- and metal-free phosphate binder that lowers the serum phosphorus levels in hemodialysis patients. Sevelamer contains multiple amines, which are partially protonated and interact with phosphate molecules through ionic and hydrogen bonding.
Naoshi, Fukushima, Nobuo, Nagano
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Efficacy of Sevelamer Hydrochloride and Sevelamer Carbonate in Hyperphosphatemia Condition-A Review
Asian Journal of Research in Chemistry, 2018Priya C. Mouli +3 more
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Glucose‐Lowering Effect of Sevelamer Hydrochloride in Hemodialysis Patients
Therapeutic Apheresis and Dialysis, 2015Ryota, Ikee, Nobuo, Hashimoto
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