Results 31 to 40 of about 56,993 (185)

Sevelamer inhibits the formation of cholesterol gallstones by modulating bile acid metabolism. [PDF]

Front Pharmacol
BackgroundThe purpose of this study was to investigate the effect and mechanism of Sevelamer hydrochloride (Sev) on cholesterol gallstone formation via the intestinal Fxr-Fgf15 signaling pathway in a mouse model.MethodsA cholesterol gallstone mouse model
Shen S, Ning M, Li M, Qian S, Ye X, Zhuang Q, Wu S, Wan X, Dong Z.   +8 more
europepmc   +2 more sources

Vitamin D Analogues and Fracture Risk in Chronic Kidney Disease: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JBMR Plus, Volume 6, Issue 4, April 2022., 2022
ABSTRACT Vitamin D receptor agonists (VDRAs) are commonly prescribed in chronic kidney disease (CKD). However, their protective effects on bone remain controversial. We performed a systematic review and meta‐analysis of randomized controlled trials (RCTs) to evaluate the effect of VDRAs on fracture risk and bone mineral density (BMD) in adult patients ...
Nada Khelifi, Louis‐Charles Desbiens, Aboubacar Sidibé, Fabrice Mac‐Way   +3 more
wiley   +1 more source

A comparative study of phosphate binders in patients with end stage kidney disease undergoing hemodialysis

Saudi Journal of Kidney Diseases and Transplantation, 2014
In the present study, a comparative evaluation of the effects of calcium acetate, calcium carbonate, sevelamer hydrochloride and lanthanum carbonate was carried out in 120 patients with end stage kidney disease (ESKD) undergoing hemodialysis. Biochemical
Viken A Prajapati, Varsha J Galani, Pankaj R Shah   +2 more
doaj   +1 more source

Long follow-up of Multiple Recurrent Calcific Masses–A rare case report of Hyperphosphatemic Familial Tumoral Calcinosis

Journal of University Medical & Dental College, 2022
Hyperphosphatemic familial tumoral calcinosis (HFTC) is an autosomal recessive benign condition of dysregulated phosphate metabolism (biallelic mutation in GLANT3, KLOTHO or FGF23) due to deficiency or resistance of intact fibroblast growth factor 23 ...
Saad Ahmed, Ayesha Saeed, Shafique Farooq , Zeeshan Yaqoob, Fatima tul Zohra, Muhammad Waqas   +5 more
doaj   +1 more source

Sevelamer hydrochloride and coronary artery calcification in chronic hemodialysis patients: a new mechanism of action

The Egyptian Journal of Internal Medicine, 2015
Background The non-calcium-based phosphate binder sevelamer hydrochloride was developed to provide chronic kidney disease patients with a polymer capable of managing hyperphosphatemia without an increase in the calcium load.
Bahaa Eldin Zayed, Hussein El-Fishawy, Amal R Al-Shihaby, Mohamed A Salem, Usama A.A. Sharaf El Din, Mona Mansour   +5 more
doaj   +1 more source

A comparison of calcium acetate/magnesium carbonate and sevelamer-hydrochloride effects on fibroblast growth factor-23 and bone markers: post hoc evaluation from a controlled, randomized study. [PDF]

Nephrol Dial Transplant, 2013
Background Different phosphate binders exert differing effects on bone mineral metabolism and levels of regulating hormones. The objective of this post hoc evaluation of the CALcium acetate MAGnesium carbonate (CALMAG) study was to compare the effects of
Covic A, Passlick-Deetjen J, Kroczak M, Büschges-Seraphin B, Ghenu A, Ponce P, Marzell B, de Francisco AL.   +7 more
europepmc   +2 more sources

PA21, a novel phosphate binder, improves renal osteodystrophy in rats with chronic renal failure.

PLoS ONE, 2017
The effects of PA21, a novel iron-based and non-calcium-based phosphate binder, on hyperphosphatemia and its accompanying bone abnormality in chronic kidney disease-mineral and bone disorder (CKD-MBD) were evaluated.
Atsushi Yaguchi, Satoshi Tatemichi, Hiroo Takeda, Mamoru Kobayashi   +3 more
doaj   +1 more source

Efficacy and Safety of Sucroferric Oxyhydroxide and Calcium Carbonate in Hemodialysis Patients

Kidney International Reports, 2018
In this phase III, open-label, single-arm, multi-center 12-week study, we evaluated the efficacy and safety of combination therapy with sucroferric oxyhydroxide (PA21) and calcium carbonate for hemodialysis patients with hyperphosphatemia.
Fumihiko Koiwa, Keitaro Yokoyama, Masafumi Fukagawa, Tadao Akizawa   +3 more
doaj   +1 more source

Polymeric Anti-Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution. [PDF]

Small
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Koshani R, Yeh SL, He Z, Narasimhalu N, Vom Steeg LG, Sim DG, Woods RJ, Read AF, Sheikhi A.   +8 more
europepmc   +2 more sources

Elderly-onset calcinosis of hyperphosphataemic familial tumoural calcinosis/hyperostosis-hyperphosphataemia syndrome: the role of comorbid scleroderma

Endocrinology, Diabetes & Metabolism Case Reports, 2023
A 73-year-old woman with type 2 diabetes mellitus was referred to our department for glycaemic control. Physical examination revealed two subcutaneous hard masses around the left shoulder and the right hip joint.
Hiroaki Iwasaki
doaj   +1 more source