Results 51 to 60 of about 56,993 (185)
Clinical Factors Associated With Serum Copper Concentration In Patients On Hemodialysis
Kidney Research and Clinical Practice, 2012 It is well known that renal insufficiency influences trace element metabolism. In particular, patients treated with hemodialysis (HD) are at higher risk for both deficiency and excess of trace elements. However, derangements of serum trace element levels
Ryota Ikee +4 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Cogent Medicine, 2016 Introduction: Lanthanum carbonate (LC) and sevelamer hydrochloride (SH) are non-calcium-based phosphate binders (NCPB), used to manage hyperphosphatemia in patients with chronic kidney disease.
Asrar Khan +6 more
doaj +1 more source
Clinical and Translational Science, Volume 18, Issue 11, November 2025.ABSTRACT Divalent cations such as calcium and ferrous sulfate interfere with the absorption of levothyroxine due to complexing. To our knowledge, the effects of magnesium on levothyroxine absorption have never been studied. The open‐label cross‐over pharmacokinetic study was conducted in 15 healthy, euthyroid adults.
Martin Christian Attinger +5 more
wiley +1 more source
A STUDY ON HYPERPHOSPHATEMIA AND EFFECT OF SEVELAMER ON CARDIAC ENZYME LEVELS IN CHRONIC KIDNEY DISEASE PATIENTS [PDF]
, 2016 Objective: Chronic Kidney Disease (CKD) is characterized by progressive loss of kidney function over a period of time. Sevelamer hydrochloride is a phosphate binding agent used to control serum phosphate levels in End Stage Renal Disease (ESRD) patients ...
S., Senthil Kumar, K., Dhivya
core +1 more source
Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation
ChemistryOpen, Volume 14, Issue 10, October 2025.The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco +2 more
wiley +1 more source
PLoS ONE, 2016 BackgroundChronic kidney disease-mineral and bone disorder (CKD-MBD) has been linked to poor health outcomes, including diminished quality and length of life. This condition is characterized by high phosphate levels and requires phosphate-lowering agents-
Nigar Sekercioglu +10 more
doaj +1 more source
Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded
MedComm, Volume 6, Issue 7, July 2025.Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin +8 more
wiley +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2012 Hyperphosphatemia is a significant risk factor for the development of ectopic calcification and coronary artery diseases in patients on hemodialysis (HD), and must be controlled with the use of phosphate binders.
Farrokhlagha Ahmadi +3 more
doaj +1 more source
Small Science, Volume 4, Issue 11, November 2024.The development of drug delivery systems is revolutionizing therapeutic progress by ensuring precise targeting and optimal drug concentrations. Nanocarriers, with their customizable properties and controlled release, overcome biological barriers to improve treatment outcomes. This study explores the potential of integrating artificial intelligence with
Minhye Kim +4 more
wiley +1 more source