The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Spatial Patterns of Diversity in Forest Birds of Peninsular India. [PDF]
Goyal N +7 more
europepmc +1 more source
On the Boundary Value of a bounded analytic Function of several complex Variables
Masatsugu TSUJI
openalex +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Commentary: The effects of complex training on performance variables in basketball players: a systematic review and meta-analysis. [PDF]
Thapa RK, Bruno J, Garcia-Carrillo E.
europepmc +1 more source
Complex symmetric weighted composition operators on the Fock space in several variables [PDF]
Pham Viet Hai, Lê Hải Khôi
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Urbanization and Child Development: Investigating Socioeconomic, Structural, and Environmental Influences on Cognitive Development. [PDF]
Sen U +5 more
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Intelligent delignification: leveraging explainable AI for ozone transport modeling and optimization. [PDF]
Rizwan M +6 more
europepmc +1 more source

